What they do:
Our tests help eradicate cancer by telling doctors whether they got…
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HQ: San Francisco, CA, United States
Top Biotech Startups in the United States
This list has 451 startups and was last updated on Oct 15, 2026. 34 of them are hiring right now. Biggest hubs: San Francisco (134), Boston (35), and New York (27). Largest teams: Benchling, Ginkgo Bioworks, and BillionToOne. Latest round: Renue Life Sciences raised $250K (Oct 14, 2026).
451 startupsPage 4 of 13
What they do:
Living therapies for pets first, and their people next
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HQ: Minneapolis, MN, United States
What they do:
Smart gels for local drug delivery to the gut
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HQ: San Francisco, CA, United States
What they do:
Shiru leverages ML to create proteins to feed the world sustainably.
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HQ: San Francisco, CA, United States
What they do:
Helping Plastic Surgeons Rebuild Fat
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HQ: Durham, NC, United States
What they do:
We make bacteria and plants that clean up pollution.
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HQ: San Francisco, CA, United States
What they do:
Activating an overlooked force in medicine - the patient.
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HQ: San Francisco, CA, United States
What they do:
Developing milk-inspired therapeutics for infectious diseases
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HQ: Davis, CA, United States
What they do:
The dynamic single-cell analysis company
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HQ: Houston, TX, United States
What they do:
Regulating the immune system to block cancer & autoimmune diseases
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HQ: Philadelphia, PA, United States
What they do:
Oral drugs to halt neurodegeneration
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HQ: San Diego, CA, United States
What they do:
Automating Data Entry for Clinical Trials
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HQ: San Francisco, CA, United States
What they do:
Next-generation biocides for sustainable agriculture at scale
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HQ: New York, NY, United States
What they do:
Enzyme design models.
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HQ: San Francisco, CA, United States
What they do:
The world's first AI-maximalist pharma company
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HQ: San Francisco, CA, United States
What they do:
A Foundation Model for Microbial Communities.
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HQ: San Francisco, CA, United States
What they do:
Evolutionary intelligence for autoimmune disease
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HQ: San Francisco, CA, United States
What they do:
YourChoice therapeutics is revolutionizing the contraceptive market…
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HQ: San Francisco, CA, United States
What they do:
Using DNA to store data.
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HQ: Boston, MA, United States
What they do:
We build better immunotherapies
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HQ: San Francisco, CA, United States
What they do:
Creating a New Class of Drugs to Address Incurable Autoimmune Diseases
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HQ: Irvine, CA, United States
What they do:
Growing micro-organs to find new drugs
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HQ: San Francisco, CA, United States
What they do:
Engineering microbes for miners to unlock billions in trapped metal
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HQ: San Francisco, CA, United States
What they do:
AI infrastructure for biosecurity
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HQ: New York, NY, United States
What they do:
Biospecimen logistics & operations layer to accelerate drug dev
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HQ: Boulder, CO, United States
What they do:
24/7 Personal Health & Longevity Companion
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HQ: San Francisco, CA, United States
What they do:
Extrapolative AI to unlock First-in-Class drugs
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HQ: San Francisco, CA, United States
What they do:
AI-native CRO for clinical trial operations
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HQ: San Francisco, CA, United States
What they do:
AI-native pharma company
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HQ: San Francisco, CA, United States
What they do:
Making chemicals 100,000x faster
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HQ: San Francisco, CA, United States
What they do:
Embodied Scientific Intelligence
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HQ: San Francisco, CA, United States
What they do:
Accelerating Histopathology for Cancer Research
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HQ: New York, NY, United States
What they do:
Sigma Genetics is a biotechnology company that is building…
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HQ: Seattle, WA, United States
What they do:
Tradewind translates scientific insight into innovative ways of…
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HQ: San Francisco, CA, United States
What they do:
Synkrino's AI, SATIS is a powerful, unbiased discovery system for…
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HQ: San Francisco, CA, United States
What they do:
mRNA therapeutics to extend healthspan entering clinical trials
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HQ: San Francisco, CA, United States