What they do:
Building programmable therapeutics for the immune system
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HQ: San Francisco, CA, United States
Top Biotech Startups in the United States
This list has 451 startups and was last updated on Oct 15, 2026. 34 of them are hiring right now. Biggest hubs: San Francisco (134), Boston (35), and New York (27). Largest teams: Benchling, Ginkgo Bioworks, and BillionToOne. Latest round: Renue Life Sciences raised $250K (Oct 14, 2026).
451 startupsPage 3 of 13
b12 Labs
Hiring
What they do:
Making hard molecules for Pharma and Biotech
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HQ: San Francisco, CA, United States
Exonic
Hiring
What they do:
Exonic is an AI-native cell and gene therapeutics company.
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HQ: San Francisco, CA, United States
Neuromorphic
Hiring
What they do:
Building robots to automate wetlabs
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HQ: San Francisco, CA, United States
What they do:
Lucy’s mission is to reduce tobacco-related harm to zero. We provide…
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HQ: Los Angeles, CA, United States
What they do:
Programmable biology company for psychoactive effect design
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HQ: San Francisco, CA, United States
What they do:
Using protein coupling to build new therapies
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HQ: San Francisco, CA, United States
What they do:
Accelerate clinical trials with real-time, actionable insights
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HQ: San Francisco, CA, United States
What they do:
Adventris makes cancer vaccines
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HQ: Baltimore, MD, United States
What they do:
We sequence your gut and build the probiotics it’s missing
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HQ: San Francisco, CA, United States
What they do:
We are using the gut microbiome to end cancer.
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HQ: San Diego, CA, United States
What they do:
Utilizing monogenic disorders to inform and solve highly complex…
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HQ: Portland, OR, United States
What they do:
XGenomes is building the sequencing technology of the future.
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HQ: Boston, MA, United States
What they do:
AI-designed Affinity Reagents
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HQ: Austin, TX, United States
What they do:
We stop cows from burping methane.
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HQ: San Francisco, CA, United States
What they do:
Combinations therapy by rational design
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HQ: New York, NY, United States
What they do:
Developing long-lasting drug formulations 50% faster
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HQ: Sacramento, CA, United States
What they do:
Elevated mRNA for transformative medicines.
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HQ: San Francisco, CA, United States
What they do:
RNA intelligence for precision medicine
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HQ: San Francisco, CA, United States
What they do:
A research lab for one
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HQ: San Francisco, CA, United States
What they do:
Enabling T cell immunotherapy discovery, development and manufacturing
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HQ: San Francisco, CA, United States
What they do:
Cancer tests based on whole genome and transcriptome data.
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HQ: New York, NY, United States
What they do:
Curative genetic medicines for kidney diseases
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HQ: New York, NY, United States
What they do:
Elevating mental health to be a part of your daily coffee ritual.
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HQ: San Francisco, CA, United States
What they do:
Genetic Medicine with Small Molecules
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HQ: San Francisco, CA, United States
What they do:
A platform to make artificial viruses as cancer therapeutics.
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HQ: New York, NY, United States
What they do:
Making 'REAL' Cow and Human Milk!
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HQ: Boston, MA, United States
What they do:
High-precision, closed-loop neuromodulation devices
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HQ: Boston, MA, United States
What they do:
Your biopharma team, from molecule design to portfolio strategy
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HQ: San Francisco, CA, United States
What they do:
Empowering every doctor and every patient to participate in research
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HQ: New York, NY, United States
What they do:
Gen-AI Designed Enzymes for Pharmaceutical Innovation
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HQ: Boston, MA, United States
What they do:
Breakthrough medicines unlocking the biology of heme
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HQ: San Francisco, CA, United States
What they do:
Gen AI molecular simulations that reproduce wetlab results
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HQ: San Francisco, CA, United States
What they do:
Full Stack Pharmaceutical Company for Personalized Peptides and GLP-1s
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HQ: San Francisco, CA, United States
What they do:
Synvivia applies chemical control over cell behavior
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HQ: San Francisco, CA, United States
What they do:
Replacing organ transplant with an infusion
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HQ: Bend, OR, United States