What they do:
Legora for AEC (Architecture, Engineering, & Construction) firms
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HQ: San Francisco, CA, United States
Top Deep Tech Startups in San Francisco
This list has 704 startups and was last updated on Oct 15, 2026. 180 of them are hiring right now. Largest teams: DoorDash, GrubMarket, and Instacart. Latest round: Aikido Technologies raised $1.72M (Oct 8, 2026).
704 startupsPage 13 of 20
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AI-Native Insurance for Frontier Tech
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HQ: San Francisco, CA, United States
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AI native platform for real estate closings
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HQ: San Francisco, CA, United States
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Virtual Reality for Training Robots
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HQ: San Francisco, CA, United States
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AI-Native Engineering Firm designing Data Centers
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HQ: San Francisco, CA, United States
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Curing cancer. Starting with dogs.
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HQ: San Francisco, CA, United States
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The AI Operating System for Auto Shops.
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HQ: San Francisco, CA, United States
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AI Brokers for Industrial Trade
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HQ: San Francisco, CA, United States
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Robots that learn on the job
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HQ: San Francisco, CA, United States
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Foundational infrastructure for Physical AI
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HQ: San Francisco, CA, United States
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Autonomous rovers to make the ‘Google Maps’ of underground utilities
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HQ: San Francisco, CA, United States
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Automatic Diagnosis & Fix for Industrial Automation Cells
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HQ: San Francisco, CA, United States
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Deploying robots to replace workers in hazardous spaces
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HQ: San Francisco, CA, United States
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AI tools for the chips your AI runs on
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HQ: San Francisco, CA, United States
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Floating nuclear powered data centers at sea.
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HQ: San Francisco, CA, United States
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World's Earliest Test for Alzheimer's Biomarkers
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HQ: San Francisco, CA, United States
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Agents running industrial enterprises from back office to shop floor
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HQ: San Francisco, CA, United States
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AI for the industries that power America.
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HQ: San Francisco, CA, United States
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A consumer brain-computer interface you can map to anything.
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HQ: San Francisco, CA, United States
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The generalist robot deployment company.
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HQ: San Francisco, CA, United States
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Precision navigation for UAVs operating without GPS.
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HQ: San Francisco, CA, United States
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On Demand CNC Prototyping
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HQ: San Francisco, CA, United States
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A foundation model for engineering physics
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HQ: San Francisco, CA, United States
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voice-first hardware interface for human-agent interaction
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HQ: San Francisco, CA, United States
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The AI decision engine for factories, warehouses and fleets
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HQ: San Francisco, CA, United States
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a phone where AI is the interface
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HQ: San Francisco, CA, United States
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Lark - AI agents that automate workflows for wholesale distributors
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HQ: San Francisco, CA, United States
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The pit crew for machines and robots.
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HQ: San Francisco, CA, United States
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Perlara: building the YC for rare disease parents
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HQ: San Francisco, CA, United States
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Universal, Pure-GPU HTML Renderer
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HQ: San Francisco, CA, United States
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Multi-agent AI for physical logistics operations
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HQ: San Francisco, CA, United States
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Redefining the Standard of Care for Iron Deficiency Anemia
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HQ: San Francisco, CA, United States
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Turning messy inboxes into ERP-Ready Data
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HQ: San Francisco, CA, United States
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AI agents for global trade compliance
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HQ: San Francisco, CA, United States
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A robotics intelligence system for metal fabrication
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HQ: San Francisco, CA, United States
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Accelerated Physics Kernels for Computational Engineering
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HQ: San Francisco, CA, United States