What they do:
Multimodal foundation models to predict uncollected patient biology
Quick facts:
HQ: San Francisco, CA, United States
Top Deep Tech Startups in San Francisco
This list has 704 startups and was last updated on Oct 15, 2026. 180 of them are hiring right now. Largest teams: DoorDash, GrubMarket, and Instacart. Latest round: Aikido Technologies raised $1.72M (Oct 8, 2026).
704 startupsPage 12 of 20
What they do:
AI teammates for logistics
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Infrastructure for Autonomous Science
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI native radars for self-driving cars
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Foundation models for 24/7 Earth Observation
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The secure training data R&D engine for physical AI
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The robot workforce for infrastructure
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Automating dexterous tasks in warehouses with AI-powered robots
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Keeping contractors on the job site, not behind a desk.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Drones that clear clouds over solar farms and weaken hurricanes
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The AI-native property management company for short-term rentals
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Using VLMs to Catch Damage
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI that runs factories.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
FDE as a platform for rebuilding critical operations in software.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The hardware-agnostic operating system for drone defense
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Research lab building the most robotic household in the world
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Humanoid robot platform for builders.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Hyper-efficient coolers for data centers
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Control lab instruments with natural language.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Building AI Native Customs Brokerages
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Deployment infrastructure for Physical AI
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI Native Sourcing Broker For Overseas Manufacturing
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Robots for vehicle maintenance.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI agent platform for home services companies.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI For The Skilled Workforce
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Your personal context, securely portable across every AI app.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Making Diamond Semiconductors
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Real-world RL environments for robotics models
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Simulating Agents Running Industrial Companies
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI-native OS for Real Estate Brokerages
Quick facts:
HQ: San Francisco, CA, United States
What they do:
OpenClaw for manufacturers
Quick facts:
HQ: San Francisco, CA, United States
What they do:
We are a multi-strategy trading firm that trains AI traders.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI-powered freight brokerage. Quote, book, and track loads in seconds.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI-native freight brokerage
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI for Construction's Back Office
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI Operating System for Wholesale Distribution
Quick facts:
HQ: San Francisco, CA, United States