Photonium
Hiring
What they do:
AI-Powered Optical Consulting & Software
Quick facts:
HQ: New York, NY, United States
Top Deep Tech Startups in the United States
This list has 1,386 startups and was last updated on Oct 15, 2026. 306 of them are hiring right now. Biggest hubs: San Francisco (704), New York (137), and Los Angeles (79). Largest teams: DoorDash, EquipmentShare, and GrubMarket. Latest round: Onebrief raised $151M (Oct 14, 2026).
1,386 startupsPage 11 of 39
Lumari
Hiring
What they do:
AI Digital Workers for Supply Chain
Quick facts:
HQ: San Francisco, CA, United States
Foundation Industries
Hiring
What they do:
We supply hard tech companies with critical components.
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HQ: San Francisco, CA, United States
What they do:
Moon Hotel -> The Intergalactic Construction Company of Earth
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HQ: Los Angeles, CA, United States
Avent
Hiring
What they do:
AI agents for industrial commerce
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HQ: San Francisco, CA, United States
What they do:
AI Agents for Hardware Engineering
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HQ: San Francisco, CA, United States
Voltair
Hiring
What they do:
Autonomous Drones for Earth Observation
Quick facts:
HQ: San Francisco, CA, United States
CellType
Hiring
What they do:
The agentic drug company. We simulate human biology.
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HQ: New York, NY, United States
What they do:
robots & software for farms
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HQ: San Francisco, CA, United States
Aseon Labs
Hiring
What they do:
Robotic pitstops for self-driving cars
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HQ: San Francisco, CA, United States
Edgerun
Hiring
What they do:
Military exoskeletons
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HQ: San Francisco, CA, United States
Pango
Hiring
What they do:
Agentic OS for e-commerce operations
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HQ: New York, NY, United States
TryNearby
Hiring
What they do:
Local creators for local businesses
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HQ: Los Angeles, CA, United States
Runtime.si
Hiring
What they do:
Evaluation Infrastructure for Robotics (YC F26)
Quick facts:
HQ: San Francisco, CA, United States
Orca Aerospace
Hiring
What they do:
AI spacecraft operators that lives onboard the vehicle
Quick facts:
HQ: San Francisco, CA, United States
Bountiful
Hiring
What they do:
An Operating System for agriculture.
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HQ: San Francisco, CA, United States
Wright Electric
Hiring
What they do:
Boeing for electric planes
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HQ: Albany, NY, United States
What they do:
Flying motorcycles
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HQ: Los Angeles, CA, United States
What they do:
Advanced Contract MFG for fast moving hardware companies
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HQ: Fort Worth, TX, United States
What they do:
IndustrialNext builds the AI brain for manufacturing –…
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HQ: San Francisco, CA, United States
What they do:
Fully autonomous defense solutions for the global edge.
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HQ: Raleigh, NC, United States
What they do:
A single point integration for secure and automated EV charging.
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HQ: San Francisco, CA, United States
What they do:
The largest freight scheduling network in the industry.
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HQ: San Francisco, CA, United States
Vendora
Hiring
What they do:
All-in-One Software for the $1T Grocery Industry
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HQ: New York, NY, United States
Metalware
Hiring
What they do:
Firmware cybersecurity
Quick facts:
HQ: San Francisco, CA, United States
Relari
Hiring
What they do:
Building dexterous robots that learn from human biomechanics
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HQ: San Francisco, CA, United States
Ultra
Hiring
What they do:
Practical, general-purpose robots for repetitive industrial tasks
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HQ: New York, NY, United States
Conductor Quantum
Hiring
What they do:
AI that operates quantum computers for scientific discovery
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HQ: San Francisco, CA, United States
Outerport
Hiring
What they do:
Design automation for industrial electrical controls
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HQ: San Francisco, CA, United States
What they do:
Manufacturing the most powerful chips, 15x faster
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HQ: San Francisco, CA, United States
Adam
Hiring
What they do:
AI Powered CAD
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HQ: San Francisco, CA, United States
Artifact
Hiring
What they do:
An Collaborative, AI-native IDE for Hardware Engineers
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HQ: Los Angeles, CA, United States
What they do:
Robots, parts & RL envs & evals - delivered in 48 hrs / pickup in SF.
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HQ: San Francisco, CA, United States
Darwin
Hiring
What they do:
Robots to build civilization
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HQ: San Francisco, CA, United States
General Astronautics
Hiring
What they do:
Superintelligent space Robots
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HQ: San Francisco, CA, United States
Fort
Hiring
What they do:
Strength Tracking Wearable
Quick facts:
HQ: San Francisco, CA, United States