What they do:
Advanced manufacturing and distribution solutions (for China-based…
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HQ: Los Angeles, CA, United States
Top Deep Tech Startups in the United States
This list has 1,386 startups and was last updated on Oct 15, 2026. 306 of them are hiring right now. Biggest hubs: San Francisco (704), New York (137), and Los Angeles (79). Largest teams: DoorDash, EquipmentShare, and GrubMarket. Latest round: Onebrief raised $151M (Oct 14, 2026).
1,386 startupsPage 9 of 39
Shape (ShapeScale)
Hiring
What they do:
ShapeScale is a personal 3D scanner and fitness tracker that…
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HQ: San Francisco, CA, United States
What they do:
Complete fare payment platform for public transportation
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HQ: San Francisco, CA, United States
What they do:
Rebellyous Foods is a food manufacturing technology and production…
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HQ: Seattle, WA, United States
What they do:
We deploy autonomous drones to 911 calls. Our software gives first…
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HQ: Houston, TX, United States
Yummy Future
Hiring
What they do:
We build robotic workforces for the food & beverage industry.
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HQ: Champaign, IL, United States
What they do:
Predictive Explorer and Driller for Critical Metal Deposits
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HQ: San Francisco, CA, United States
What they do:
B2B SaaS for insurance damage repair contractors.
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HQ: Downers Grove, IL, United States
Ohm
Hiring
What they do:
Ohm helps engineering teams accelerate hardware development & testing.
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HQ: San Francisco, CA, United States
Clad
Hiring
What they do:
Project management software for building infrastructure.
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HQ: New York, NY, United States
Nectar
Hiring
What they do:
Manage energy cost & usage with AI for facility & sustainability teams
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HQ: San Francisco, CA, United States
Guac
Hiring
What they do:
AI-powered forecasting & replenishment for grocery
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HQ: New York, NY, United States
Navier AI
Hiring
What they do:
Agent-Driven Engineering
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HQ: San Francisco, CA, United States
Tuesday Labs
Hiring
What they do:
Delightful robots
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HQ: New York, NY, United States
Yondu
Hiring
What they do:
Robots to Automate Fulfillment
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HQ: Los Angeles, CA, United States
Forge
Hiring
What they do:
AI native freight forwarder and customs broker
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HQ: New York, NY, United States
Indemni
Hiring
What they do:
Cargo Theft and Fraud Prevention Platform
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HQ: San Francisco, CA, United States
Saphira AI
Hiring
What they do:
The Enablement Layer for Physical AI
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HQ: San Francisco, CA, United States
Theseus
Hiring
What they do:
GPS Denied Navigation for Drones
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HQ: San Francisco, CA, United States
Innate
Hiring
What they do:
Personal AI Robots
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HQ: San Francisco, CA, United States
Apolink
Hiring
What they do:
24/7 satellite connectivity in low Earth orbit
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HQ: San Francisco, CA, United States
What they do:
Building the open source smart glasses operating system.
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HQ: San Francisco, CA, United States
MorphoAI
Hiring
What they do:
Software tool for designing robots and machines
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HQ: New York, NY, United States
Cascade Space
Hiring
What they do:
Commercial alternative to the Deep Space Network
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HQ: San Francisco, CA, United States
Parametric
Hiring
What they do:
Physical businesses that run themselves
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HQ: San Francisco, CA, United States
Verne Robotics
Hiring
What they do:
AI models that teach robots new skills in hours
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HQ: San Francisco, CA, United States
What they do:
Reshoring critical metal production
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HQ: San Francisco, CA, United States
RamAIn
Hiring
What they do:
RamAIn - AI Employees with a computer to perform business tasks just…
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HQ: San Francisco, CA, United States
What they do:
Telepresence robots
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HQ: San Francisco, CA, United States
What they do:
Waze for parking
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HQ: San Francisco, CA, United States
What they do:
Labdoor is building the trusted online drugstore.
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HQ: San Francisco, CA, United States
What they do:
Flirtey is the world’s first commercial drone delivery service and…
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HQ: Blountville, TN, United States
What they do:
We make beautiful connected light switches that allow you to control…
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HQ: Seattle, WA, United States
What they do:
E-commerce 2.0
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HQ: San Francisco, CA, United States
What they do:
Organic and gourmet high-protein meals, designed for longevity.
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HQ: San Francisco, CA, United States
Arpari
Hiring
What they do:
Multibank treasury management
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HQ: New York, NY, United States