What they do:
We produce & sell stainless steel water bottles that enables people…
Quick facts:
HQ: London, United Kingdom
Top Deep Tech Startups
This list has 1,861 startups and was last updated on Oct 15, 2026. 377 of them are hiring right now. Biggest hubs: San Francisco (704), New York (137), and Los Angeles (79). Largest teams: Breadfast, DoorDash, and EquipmentShare. Latest round: Scimplify raised $25M (Oct 15, 2026).
Survival statistics →1,040 open roles →
1,861 startupsPage 32 of 52
What they do:
The operating system for commercial buildings.
Quick facts:
HQ: Niagara Falls, NY, United States
What they do:
Perlara: building the YC for rare disease parents
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Prime Lightworks Inc. manufactures electric propulsion systems for…
Quick facts:
HQ: Culver City, CA, United States
What they do:
Universal, Pure-GPU HTML Renderer
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Multi-agent AI for physical logistics operations
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Pelvic floor fitness made easy
Quick facts:
HQ: Chicago, IL, United States
What they do:
Redefining the Standard of Care for Iron Deficiency Anemia
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Faster processors for solving NP-complete problems
Quick facts:
HQ: San Diego, CA, United States
What they do:
Specialized agents for real work
Quick facts:
HQ: Los Angeles, CA, United States
What they do:
Building and Protecting an Exciting Future
Quick facts:
HQ: Los Angeles, CA, United States
What they do:
Turning messy inboxes into ERP-Ready Data
Quick facts:
HQ: San Francisco, CA, United States
What they do:
OS for global e-commerce expansion of brands & manufacturers
Quick facts:
What they do:
Power-ready land for AI data centers
Quick facts:
HQ: New York, NY, United States
What they do:
AI agents for global trade compliance
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI for the physical world
Quick facts:
HQ: Los Angeles, CA, United States
What they do:
Tools for the next era of physical automation.
Quick facts:
HQ: Germany
What they do:
Infrastructure Cartography
Quick facts:
HQ: Boston, MA, United States
What they do:
A robotics intelligence system for metal fabrication
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Accelerated Physics Kernels for Computational Engineering
Quick facts:
HQ: San Francisco, CA, United States
What they do:
US-Made Parts for Robots
Quick facts:
HQ: Austin, TX, United States
What they do:
AI-native, hardware procurement marketplace
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Tankless Dive Gear - Breath Autonomy at Sea, Land & Space
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI agent that manages manufacturing operations over text
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Camera-free AI glasses. Your AI, out in the world.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Robots to maintain and assemble data centers
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Vaccines for any cancer or infection in weeks.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
An agentic phone that does your busywork
Quick facts:
HQ: Germany
What they do:
Force-sensing wristband for training robotic AI
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Actuators for Physical AI
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Android for drones
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Protonet provides the easiest way for a small business to run its own…
Quick facts:
YC W16Early stage
What they do:
ApolloShield is a system that detects unwanted drones and drives them…
Quick facts:
YC S16Early stage
What they do:
ISP for Africa
Quick facts:
YC W17Growth stage
What they do:
We help retailers and restaurant chains manage repairs and…
Quick facts:
HQ: San Francisco, CA, United States
YC S18Early stage
What they do:
The Future of Supply Chain Data Tracking and Visibility
Quick facts:
HQ: London, United Kingdom
YC W19Growth stage