What they do:
Brain Longevity
Quick facts:
HQ: San Francisco, CA, United States
Top Digital Health Startups in San Francisco
This list has 190 startups and was last updated on Oct 15, 2026. 58 of them are hiring right now. Largest teams: Truepill, Clipboard, and Athelas. Latest round: Malama Health raised $5.32M (Feb 26, 2026).
190 startupsPage 2 of 6
What they do:
The first digital mental health system for youth
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HQ: San Francisco, CA, United States
Lamar Health
Hiring
What they do:
Take Care of Shitty Paperwork for Expensive Drugs
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HQ: San Francisco, CA, United States
Toothy AI
Hiring
What they do:
AI for insurance verification & billing at dental clinics
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HQ: San Francisco, CA, United States
Sunflower
Hiring
What they do:
We are building an AI-native telemedicine clinic for addiction. 🌻
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HQ: San Francisco, CA, United States
What they do:
Predicting and preventing heart disease.
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HQ: San Francisco, CA, United States
Brighterway
Hiring
What they do:
Streamlining the medical record review process in workers comp
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HQ: San Francisco, CA, United States
Legion Health
Hiring
What they do:
Autonomous medical care
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HQ: San Francisco, CA, United States
What they do:
24/7 pediatric clinic in every family's living room
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HQ: San Francisco, CA, United States
What they do:
Automating Healthcare Revenue Cycle Management with AI Workforce
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HQ: San Francisco, CA, United States
Syntra
Hiring
What they do:
Faster healthcare payments
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HQ: San Francisco, CA, United States
What they do:
FidoCure® is the leader in Precision Medicine for Canine Oncology.
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HQ: San Francisco, CA, United States
SafeBeat
Hiring
What they do:
First ECG AI to go beyond diagnostics and recommend treatment
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HQ: San Francisco, CA, United States
Shimmer
Hiring
What they do:
1:1 ADHD coaching, 5-10X More affordable than alternatives
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HQ: San Francisco, CA, United States
Careforce
Hiring
What they do:
AI Workers for Healthcare Orgs to Find, Call & Schedule More Patients.
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HQ: San Francisco, CA, United States
What they do:
Longevity for the 99%.
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HQ: San Francisco, CA, United States
Clicks Health
Hiring
What they do:
AI agents for your healthcare back-office operations.
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HQ: San Francisco, CA, United States
What they do:
API for healthcare compliance
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HQ: San Francisco, CA, United States
What they do:
The smart testing platform that unlocks digital health at home.
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HQ: San Francisco, CA, United States
Sonia
Hiring
What they do:
Validated mental health support in your pocket, anytime.
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HQ: San Francisco, CA, United States
What they do:
The Human Diagnosis Project.
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HQ: San Francisco, CA, United States
What they do:
The free HIV vaccine.
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HQ: San Francisco, CA, United States
Rinse
Hiring
What they do:
We're building the One Medical for dental
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HQ: San Francisco, CA, United States
Cair Health
Hiring
What they do:
AI Agents for Healthcare RCM
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HQ: San Francisco, CA, United States
Dodo
Hiring
What they do:
AI agents that handle communications for clinics
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HQ: San Francisco, CA, United States
Vera Health
Hiring
What they do:
AI-powered clinical decision support for healthcare providers
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HQ: San Francisco, CA, United States
Asteroid
Hiring
What they do:
The integration layer for healthcare: EHRs, payer portals & more
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HQ: San Francisco, CA, United States
Novoflow
Hiring
What they do:
Computer-using agents for healthcare operations
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HQ: San Francisco, CA, United States
What they do:
A social app for phone calls. Express yourself and make real friends.
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HQ: San Francisco, CA, United States
What they do:
Pediatric digital therapeutic for the +100M families in the US
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HQ: San Francisco, CA, United States
What they do:
Self-learning care for complex illness
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HQ: San Francisco, CA, United States
Shasta Health
Hiring
What they do:
Helping rehab practices book more patients
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HQ: San Francisco, CA, United States
Andy AI
Hiring
What they do:
Faster clinical documentation for home health nurses
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HQ: San Francisco, CA, United States
Adentris
Hiring
What they do:
Real-time AI Compliance & Revenue Integrity for Medical Providers
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HQ: San Francisco, CA, United States
Janeen
Hiring
What they do:
Prior auths and benefits investigation for infusion clinics
Quick facts:
HQ: San Francisco, CA, United States
Health Harbor
Hiring
What they do:
Using generative AI to call insurance for healthcare clinics
Quick facts:
HQ: San Francisco, CA, United States