What they do:
Get measured by your phone in under 30 seconds for perfect fitting…
Quick facts:
HQ: Salt Lake City, UT, United States
Top E-commerce Startups in the United States
This list has 279 startups and was last updated on Oct 15, 2026. 53 of them are hiring right now. Biggest hubs: San Francisco (142), New York (56), and Los Angeles (20). Largest teams: DoorDash, GrubMarket, and Instacart. Latest round: Astraea, Inc./DE raised $175K (Oct 14, 2026).
279 startupsPage 3 of 8
What they do:
E-commerce 2.0
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Dollar Shave Club as a platform.
Quick facts:
HQ: Seattle, WA, United States
Converge
Hiring
What they do:
All-in-one marketing measurement for B2C
Quick facts:
HQ: New York, NY, United States
Anglera
Hiring
What they do:
AI-Powered Product Data Enrichment
Quick facts:
HQ: San Francisco, CA, United States
What they do:
StyleUp brings effortless joy to getting dressed with daily,…
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The secret backbone of e-commerce.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Buying and owning indoor potted plants made easy.
Quick facts:
HQ: Los Angeles, CA, United States
Pillar
Hiring
What they do:
All-In-One Creator Store
Quick facts:
HQ: San Francisco, CA, United States
Turing Labs Inc.
Hiring
What they do:
AI for R&D of consumer brands like P&G to develop better products
Quick facts:
HQ: San Francisco, CA, United States
BetterBasket
Hiring
What they do:
Smart grocery pricing with AI
Quick facts:
HQ: San Francisco, CA, United States
Channel3
Hiring
What they do:
Database of every product on the internet
Quick facts:
HQ: New York, NY, United States
Pango
Hiring
What they do:
Agentic OS for e-commerce operations
Quick facts:
HQ: New York, NY, United States
What they do:
Opentable for the world's top restaurants; we help them increase…
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI Agent for Home Design
Quick facts:
HQ: Los Angeles, CA, United States
Vendora
Hiring
What they do:
All-in-One Software for the $1T Grocery Industry
Quick facts:
HQ: New York, NY, United States
What they do:
AppLovin for the food & CPG
Quick facts:
HQ: New York, NY, United States
Scout
Hiring
What they do:
AI insights for consumer products
Quick facts:
HQ: San Francisco, CA, United States
GloGlo
Hiring
What they do:
Curing and preventing type 1 diabetes
Quick facts:
HQ: San Francisco, CA, United States
Refactor
Hiring
What they do:
Deploying secure and reliable AI agents across healthcare, retail,…
Quick facts:
HQ: San Francisco, CA, United States
Amboras
Hiring
What they do:
AI Native Shopify
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Lucy’s mission is to reduce tobacco-related harm to zero. We provide…
Quick facts:
HQ: Los Angeles, CA, United States
Hellometer
Hiring
What they do:
Making fast food faster
Quick facts:
HQ: Los Angeles, CA, United States
What they do:
Recover failed subscription payments to increase retention and LTV
Quick facts:
HQ: Boston, MA, United States
Layers
Hiring
What they do:
Improve your appearance by measuring, understanding, and tracking…
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Frictionless payments via SMS
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The fastest way to sell online.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
"Name Your Price" for products
Quick facts:
HQ: New York, NY, United States
What they do:
Software eats custom framing
Quick facts:
HQ: New York, NY, United States
What they do:
Markhor is a DTC company that works with craftsmen to make shoes and…
Quick facts:
HQ: San Francisco, CA, United States
Wildcard
Hiring
What they do:
AEO/GEO for E-Commerce and Retail
Quick facts:
HQ: San Francisco, CA, United States
YC W25Early stage
What they do:
AI-Native Restaurant POS
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Sell beyond the store.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
A direct to consumer marketplace and influencer network for brands
Quick facts:
HQ: Los Angeles, CA, United States
What they do:
One app for stress-free shopping, cooking, and meal planning.
Quick facts:
HQ: Missoula, MT, United States
What they do:
Skyscrape makes temperature-responsive insulation
Quick facts:
HQ: Portland, OR, United States