What they do:
A direct to consumer marketplace and influencer network for brands
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HQ: Los Angeles, CA, United States
Top E-commerce Startups
This list has 415 startups and was last updated on Oct 15, 2026. 69 of them are hiring right now. Biggest hubs: San Francisco (142), New York (56), and Los Angeles (20). Largest teams: Breadfast, DoorDash, and GrubMarket. Latest round: Astraea, Inc./DE raised $175K (Oct 14, 2026).
Survival statistics →250 open roles →
415 startupsPage 6 of 12
What they do:
Helping realtors showcase the full potential of their properties
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What they do:
One app for stress-free shopping, cooking, and meal planning.
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HQ: Missoula, MT, United States
What they do:
Skyscrape makes temperature-responsive insulation
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HQ: Portland, OR, United States
What they do:
Clinical skincare tested on diverse skin, now available in Sephora.
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HQ: San Francisco, CA, United States
What they do:
Building Shein of Home: tech-driven, design-mfr Home Lifestyle Brand
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HQ: Singapore
What they do:
Investing app for Muslims
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HQ: Manama, Bahrain
What they do:
Neobank for e-commerce businesses
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HQ: New York, NY, United States
What they do:
AI teammate for finance and operations teams at consumer brands
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HQ: New York, NY, United States
What they do:
The fastest way to launch product catalogs.
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HQ: London, United Kingdom
What they do:
The reliability platform for last-mile delivery
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HQ: New York, NY, United States
What they do:
AI Agents for E-commerce Customer Support
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HQ: Amsterdam, Netherlands
What they do:
AI agents that recover lost revenue through real conversations.
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HQ: Mexico City, Mexico
What they do:
Custom-made artwork from artists e-commerce marketplace.
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HQ: Tokyo, Japan
What they do:
Fastest, easiest, and most affordable way for small business owners…
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HQ: San Francisco, CA, United States
What they do:
Encarte is building 1-click checkout for all online stores.
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HQ: San Francisco, CA, United States
What they do:
B2B payments network in India
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What they do:
Subscriptions for neighborhood businesses
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HQ: San Francisco, CA, United States
What they do:
Supply chain finance for consumer brands
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HQ: Honolulu, HI, United States
What they do:
Automated phone ordering system for restaurants
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HQ: San Francisco, CA, United States
What they do:
D2C Skincare for Eczema
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HQ: San Francisco, CA, United States
What they do:
KemNet supplies reformulated drugs for specific groups of patients.
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What they do:
The operating system for the car wash industry.
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HQ: Temecula, CA, United States
What they do:
API & SDK for RCS (the next-generation of texting)
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HQ: San Francisco, CA, United States
What they do:
Turn the web into structured data
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HQ: San Francisco, CA, United States
What they do:
AI agents for conversational commerce
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HQ: San Francisco, CA, United States
What they do:
A vintage marketplace curated by AI
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HQ: New York, NY, United States
What they do:
iMessage revenue channel for DTC brands that brings customers back
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HQ: San Francisco, CA, United States
What they do:
AI-run consumer brands
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HQ: Seoul, South Korea
What they do:
The AI revenue platform for D2C brands
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HQ: San Francisco, CA, United States
What they do:
Building New Anti-Aging Ingredients for Skincare
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HQ: San Francisco, CA, United States
What they do:
OS for global e-commerce expansion of brands & manufacturers
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What they do:
AI-native sales agents that run marketplaces
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HQ: San Francisco, CA, United States
What they do:
Analytics stack for omnichannel retailers and brands
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HQ: San Francisco, CA, United States
YC W14Early stage
What they do:
Community-driven marketplace for sneakers.
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HQ: Los Angeles, CA, United States
YC W15Early stage
What they do:
We help retailers and restaurant chains manage repairs and…
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HQ: San Francisco, CA, United States
YC S18Early stage