What they do:
A foundation model for engineering physics
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HQ: San Francisco, CA, United States
Top Startups in California
This list has 3,698 startups and was last updated on Oct 15, 2026. 827 of them are hiring right now. Biggest hubs: San Francisco (3,173), Los Angeles (197), and San Diego (39). Largest teams: DoorDash, Stripe, and Airbnb. Latest round: Renue Life Sciences raised $250K (Oct 14, 2026).
3,698 startupsPage 58 of 103
What they do:
Turn any website into an MCP for your agents, in minutes
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HQ: San Francisco, CA, United States
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Reconero helps police officers automate their workflows with AI
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HQ: San Francisco, CA, United States
What they do:
Infra to make AI safe enough to practice medicine
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HQ: San Francisco, CA, United States
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voice-first hardware interface for human-agent interaction
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HQ: San Francisco, CA, United States
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Turns EHR data into study-ready datasets for hospital research teams
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HQ: San Francisco, CA, United States
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The AI decision engine for factories, warehouses and fleets
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HQ: San Francisco, CA, United States
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Accelerating scaled plastics with additive technologies
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HQ: El Segundo, CA, United States
What they do:
reducing agent reasoning into a graph search problem
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HQ: San Francisco, CA, United States
What they do:
Cursor for GTM
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HQ: San Francisco, CA, United States
What they do:
Your health plan should get better year-round. Not just once a year.
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HQ: San Francisco, CA, United States
What they do:
a phone where AI is the interface
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HQ: San Francisco, CA, United States
What they do:
Training Data For Speech Models.
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HQ: San Francisco, CA, United States
What they do:
Lark - AI agents that automate workflows for wholesale distributors
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HQ: San Francisco, CA, United States
What they do:
Cloud development environments for AI coding
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HQ: San Francisco, CA, United States
What they do:
The pit crew for machines and robots.
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HQ: San Francisco, CA, United States
What they do:
100% EV fair gacha
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HQ: San Francisco, CA, United States
What they do:
Collaborate with an artist to commission original artwork you'll live…
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HQ: San Francisco, CA, United States
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Tumult is building the next generation of apps for web design. Our…
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HQ: San Francisco, CA, United States
What they do:
Buxfer helps you make better spending decisions by making it easy to…
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HQ: San Francisco, CA, United States
What they do:
NewsBlur is a personalized news reader
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HQ: San Francisco, CA, United States
What they do:
Become the leader your company needs.
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HQ: San Francisco, CA, United States
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Perlara: building the YC for rare disease parents
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HQ: San Francisco, CA, United States
What they do:
Prime Lightworks Inc. manufactures electric propulsion systems for…
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HQ: Culver City, CA, United States
What they do:
Digital Co-op Renters Insurance = half the price, better coverage.
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HQ: San Francisco, CA, United States
What they do:
FollowUpThen is an email-based personal assistant that sends you…
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HQ: San Francisco, CA, United States
What they do:
Universal, Pure-GPU HTML Renderer
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HQ: San Francisco, CA, United States
What they do:
Build UI fast.
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HQ: San Francisco, CA, United States
What they do:
Building New Anti-Aging Ingredients for Skincare
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HQ: San Francisco, CA, United States
What they do:
Multi-agent AI for physical logistics operations
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HQ: San Francisco, CA, United States
What they do:
Redefining the Standard of Care for Iron Deficiency Anemia
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HQ: San Francisco, CA, United States
What they do:
AI Agents for Healthcare Intake
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HQ: San Francisco, CA, United States
What they do:
Stealth AI Lab
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HQ: San Francisco, CA, United States
What they do:
AI SDR
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HQ: San Francisco, CA, United States
What they do:
Faster processors for solving NP-complete problems
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HQ: San Diego, CA, United States
What they do:
AI Agent for Billpay platforms to pay invoices with virtual cards
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HQ: San Francisco, CA, United States