Quick facts:
HQ: Weston, MA, United States
Incorporated: 2022
Funding:
$4.8M · Equity · Jan 2026
Top Startups in Massachusetts
This list has 228 startups and was last updated on Oct 15, 2026. 15 of them are hiring right now. Biggest hubs: Boston (138), Cambridge (24), and Waltham (8). Largest teams: Ginkgo Bioworks, Modern Health, and Sendwave. Latest round: ArthroMeda raised $8.75M (Oct 13, 2026).
228 startupsPage 5 of 7
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HQ: Waltham, MA, United States
Incorporated: 2024
Funding:
$4.58M · Equity · Apr 2026
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HQ: Somerville, MA, United States
Incorporated: 2025
Funding:
$4.5M · Equity · Feb 2026
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HQ: Waltham, MA, United States
Incorporated: 2024
Funding:
$4.35M · Equity · Mar 2026
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HQ: Cambridge, MA, United States
Incorporated: 2025
Funding:
$4.11M · Equity · Jan 2026
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HQ: Southborough, MA, United States
Incorporated: 2026
Funding:
$4.1M · Equity · Jun 2026
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HQ: Somerville, MA, United States
Funding:
$3.96M · Equity · Oct 2026
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HQ: Dedham, MA, United States
Funding:
$3.95M · Debt · Jun 2026
Quick facts:
HQ: Waltham, MA, United States
Incorporated: 2024
Funding:
$3.77M · Equity · May 2026
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HQ: Groton, MA, United States
Funding:
$3.52M · Equity · Mar 2026
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HQ: Worcester, MA, United States
Incorporated: 2021
Funding:
$3.16M · Equity + debt · Mar 2026
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HQ: Boston, MA, United States
Incorporated: 2023
Funding:
$3M · Debt · Jun 2026
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HQ: Boston, MA, United States
Incorporated: 2025
Funding:
$3M · Equity · Jan 2026
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HQ: Cambridge, MA, United States
Incorporated: 2023
Funding:
$3M · Equity · Mar 2026
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HQ: Austin, MA, United States
Incorporated: 2025
Funding:
$2.9M · Equity · Mar 2026
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HQ: Boston, MA, United States
Incorporated: 2023
Funding:
$2.8M · Equity · Feb 2026
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HQ: Chestnut Hill, MA, United States
Incorporated: 2025
Funding:
$2.63M · Equity · Oct 2026
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HQ: Boston, MA, United States
Incorporated: 2025
Funding:
$2.6M · Equity · Jan 2026
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HQ: Lowell, MA, United States
Incorporated: 2022
Funding:
$2.5M · Options · Jun 2026
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HQ: Hingham, MA, United States
Incorporated: 2026
Funding:
$2.39M · Equity · Mar 2026
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HQ: Lowell, MA, United States
Incorporated: 2024
Funding:
$2.33M · Equity · Apr 2026
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HQ: Lexington, MA, United States
Incorporated: 2024
Funding:
$2.2M · Equity · May 2026
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HQ: Amherst, MA, United States
Incorporated: 2021
Funding:
$2.09M · Equity · Mar 2026
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HQ: Boston, MA, United States
Incorporated: 2023
Funding:
$2.06M · Equity · Feb 2026
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HQ: Boston, MA, United States
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$1.89M · Equity · Apr 2026
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HQ: Boston, MA, United States
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$1.8M · Equity · Oct 2026
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HQ: Arlington, MA, United States
Funding:
$1.75M · Equity · Mar 2026
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HQ: Needham, MA, United States
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$1.5M · Equity · May 2026
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HQ: Boston, MA, United States
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$1.5M · SAFE · Mar 2026
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HQ: Watertown, MA, United States
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$1.39M · Equity · Mar 2026
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HQ: Norwood, MA, United States
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$1.3M · Equity · Jan 2026
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HQ: Arlington, MA, United States
Incorporated: 2026
Funding:
$1.3M · SAFE · Jun 2026
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HQ: Groton, MA, United States
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$1.29M · Equity · Apr 2026
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HQ: Boston, MA, United States
Incorporated: 2023
Funding:
$1.28M · Debt · Apr 2026
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HQ: Mansfield, MA, United States
Funding:
$1.2M · Debt · Oct 2026
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HQ: Brookline, MA, United States
Incorporated: 2025
Funding:
$1M · Equity · Jun 2026