Quick facts:
HQ: Cambridge, MA, United States
Incorporated: 2025
Funding:
$1M · SAFE · May 2026
Top Startups in Massachusetts
This list has 228 startups and was last updated on Oct 15, 2026. 15 of them are hiring right now. Biggest hubs: Boston (138), Cambridge (24), and Waltham (8). Largest teams: Ginkgo Bioworks, Modern Health, and Sendwave. Latest round: ArthroMeda raised $8.75M (Oct 13, 2026).
228 startupsPage 6 of 7
Quick facts:
HQ: Framingham, MA, United States
Funding:
$1M · Equity · Apr 2026
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HQ: Boston, MA, United States
Incorporated: 2024
Funding:
$1M · Equity · Feb 2026
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HQ: Watertown, MA, United States
Incorporated: 2025
Funding:
$970K · Equity · Oct 2026
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HQ: Boston, MA, United States
Funding:
$850K · Options · Oct 2026
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HQ: Stow, MA, United States
Incorporated: 2023
Funding:
$759K · Debt · Oct 2026
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HQ: Pembroke, MA, United States
Funding:
$681K · Equity · Oct 2026
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HQ: Burlington, MA, United States
Incorporated: 2025
Funding:
$238K · Equity · Oct 2026
Quick facts:
HQ: Boston, MA, United States
Incorporated: 2025
Funding:
$100K · SAFE · Oct 2026
Cloudant
Acquired
What they do:
NoSQL Database-aaS. Acquired by IBM in 2014. Now IBM Cloud Data…
Quick facts:
HQ: Boston, MA, United States
Vendr
Acquired
What they do:
The AI negotiation agent to help you save money on SaaS.
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HQ: Boston, MA, United States
Sandbox Banking
Acquired
What they do:
Low-code integration platform for banking
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HQ: Boston, MA, United States
Moltin
Acquired
What they do:
eCommerce building blocks through simple APIs for websites & apps.…
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HQ: Boston, MA, United States
Ascen
Acquired
What they do:
EOR for the staffing industry
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HQ: Boston, MA, United States
One Codex
Acquired
What they do:
Data platform for metagenomics and the microbiome.
Quick facts:
HQ: Boston, MA, United States
Impactive (formerly Outvote)
Acquired
What they do:
Political/civic tech helping progressive campaigns organize & mobilize
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HQ: Boston, MA, United States
Medumo
Acquired
What they do:
We manage patient instructions for hospitals
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HQ: Boston, MA, United States
Gaiascope
Acquired
What they do:
SaaS that helps renewables & energy storage operate more profitably
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HQ: Boston, MA, United States
Swipehouse
Acquired
What they do:
Meet other creators. Get daily matches. Find brand deals.
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HQ: Boston, MA, United States
Pretty Instant
Acquired
What they do:
Inventor of the first roaming-photo booth + pro photography platform
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HQ: Boston, MA, United States
Bytebot
Acquired
What they do:
Bytebot is the open source container for AI desktop agents.
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HQ: Boston, MA, United States
Embedly
Acquired
What they do:
Embedly provides a platform and suite of tools to make embedding and previewing links simple. Embedly helps publishers and consumers manage embed codes from…
Quick facts:
HQ: Boston, MA, United States
Kiko
Acquired
What they do:
We're the best online calendar solution to ever exist. Period.
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HQ: Boston, MA, United States
YC S05Early stage
Hunter2
Acquired
What they do:
Hunter2 trains engineering teams in application security through…
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HQ: Boston, MA, United States
YC W18Early stage
Reverie Labs
Shut down
What they do:
Engineering next-generation, brain-penetrant cancer therapies.
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HQ: Boston, MA, United States
SenpAI.GG
Shut down
What they do:
Personal gaming coach for PC gamers globally
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HQ: Boston, MA, United States
Multiverse
Shut down
What they do:
Multiverse is a web-based game creation system inspired by Dungeons &…
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HQ: Boston, MA, United States
CoVerified
Shut down
What they do:
Using infection data to keep organizations safe
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HQ: Boston, MA, United States
Radix Labs
Shut down
What they do:
Operating systems for biology labs
Quick facts:
HQ: Boston, MA, United States
Mindmesh
Shut down
What they do:
Mindmesh is the virtual desk that puts you in control.
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HQ: Boston, MA, United States
Ubiq
Shut down
What they do:
Screen-sharing for enterprise conference rooms
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HQ: Boston, MA, United States
Goodly
Shut down
What they do:
Student loan repayment as an employee benefit.
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HQ: Boston, MA, United States
Zanbazaar
Shut down
What they do:
Community-curated catalogs for product recommendations
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HQ: Boston, MA, United States
WireOver
Shut down
What they do:
Really secure file sending for big files.
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HQ: Boston, MA, United States
Hipmob
Shut down
What they do:
Customer communication for iOS and Android developers - an in-app…
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HQ: Boston, MA, United States
Ticket Stumbler
Shut down
What they do:
TicketStumbler is a secondary ticket market search engine and comparison website. They search through thousands of ticket listings from hundreds of brokers…
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HQ: Boston, MA, United States