What they do:
Blood Test for Early Detection of Ovarian Cancer
Quick facts:
HQ: Denver, CO, United States
Top Startups in the United States
This list has 6,416 startups and was last updated on Oct 16, 2026. 1,188 of them are hiring right now. Biggest hubs: San Francisco (3,181), New York (859), and Los Angeles (198). Largest teams: DoorDash, Stripe, and Airbnb. Latest round: High Street Holdco raised $3.5M (Oct 15, 2026).
6,416 startupsPage 19 of 179
What they do:
Subscription infrastructure & paywall experimentation for mobile apps
Quick facts:
HQ: New York, NY, United States
Serif Health
Hiring
What they do:
Healthcare Price Transparency APIs and Data Products
Quick facts:
HQ: Los Angeles, CA, United States
Replo
Hiring
What they do:
Sell anything
Quick facts:
HQ: San Francisco, CA, United States
Parallel Bio
Hiring
What they do:
Using the immune system to cure disease
Quick facts:
HQ: San Francisco, CA, United States
OneSchema
Hiring
What they do:
The AI Cowork for big data
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HQ: San Francisco, CA, United States
What they do:
We make Orca, MIT open source terminal-based agent orchestrator
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HQ: San Francisco, CA, United States
Gym Class
Hiring
What they do:
Connecting the world by simulating it
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The real-time retrieval engine for search, feeds, and agents.
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HQ: New York, NY, United States
Medplum
Hiring
What they do:
API first electronic health record (EHR) that is open source
Quick facts:
HQ: San Francisco, CA, United States
Pasito
Hiring
What they do:
AI agents for insurance and benefits
Quick facts:
HQ: New York, NY, United States
HOMLI
Hiring
What they do:
Sell your home without brokers
Quick facts:
HQ: New York, NY, United States
Axle
Hiring
What they do:
AI-native clearinghouse for insurance
Quick facts:
HQ: New York, NY, United States
loopfour
Hiring
What they do:
Workflow automation, without AI hallucinations.
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HQ: San Francisco, CA, United States
What they do:
Production-ready document processing
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HQ: New York, NY, United States
Vector
Hiring
What they do:
Advertising for the new internet
Quick facts:
HQ: Boston, MA, United States
LiteLLM
Hiring
What they do:
Call every LLM API like it's OpenAI [100+ LLMs]
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HQ: San Francisco, CA, United States
Artie
Hiring
What they do:
Software that streams data from databases to warehouses in real-time
Quick facts:
HQ: San Francisco, CA, United States
Readily
Hiring
What they do:
AI Compliance Platform for Healthcare Organizations
Quick facts:
HQ: San Francisco, CA, United States
FleetWorks
Hiring
What they do:
AI enabled marketplace matching trucks with jobs
Quick facts:
HQ: San Francisco, CA, United States
Tamarind Bio
Hiring
What they do:
AI Inference Platform for Drug Discovery
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Frontier coding data for training and evaluating LLMs
Quick facts:
HQ: San Francisco, CA, United States
Arva AI
Hiring
What they do:
AI for critical banking operations
Quick facts:
HQ: New York, NY, United States
Contrario
Hiring
What they do:
AI hiring platform powered by expert recruiters
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HQ: San Francisco, CA, United States
Volantio
Hiring
What they do:
Post-booking revenue and capacity optimization for airlines…
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HQ: Atlanta, GA, United States
What they do:
Embedded Analytics and Data Sharing Platform
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HQ: New York, NY, United States
What they do:
The easiest way to set up a modern data stack
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HQ: San Francisco, CA, United States
What they do:
The fastest way to ship airtight AI
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HQ: San Francisco, CA, United States
Merlin AI
Hiring
What they do:
AI powered ERP for Construction
Quick facts:
HQ: Los Angeles, CA, United States
9 Mothers
Hiring
What they do:
Counter Drone Systems. $1.6m sales. We delivered for the DoW.
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HQ: Austin, TX, United States
What they do:
The financial foundation for every real estate development decision
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HQ: Denver, CO, United States
What they do:
Rest is an AI sleep coach that helps you fix your sleep for good,…
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HQ: San Francisco, CA, United States
JITX
Hiring
What they do:
Automatic circuit board design.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The funnel builder built for health & wellness brands.
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HQ: San Francisco, CA, United States
What they do:
The fashion product engineering intelligence
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HQ: San Francisco, CA, United States
Porter
Hiring
What they do:
Easiest way to deploy on AWS/GCP/Azure
Quick facts:
HQ: New York, NY, United States