What they do:
Let agents talk to your customers
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HQ: San Francisco, CA, United States
Top Startups in the United States
This list has 6,379 startups and was last updated on Oct 15, 2026. 1,190 of them are hiring right now. Biggest hubs: San Francisco (3,173), New York (858), and Los Angeles (197). Largest teams: DoorDash, Stripe, and Airbnb. Latest round: Lungpacer Medical raised $7.83M (Oct 14, 2026).
6,379 startupsPage 61 of 178
What they do:
AI-Native Investor Relations
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HQ: San Francisco, CA, United States
What they do:
Company Brain.
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HQ: San Francisco, CA, United States
What they do:
We're building robot birds for surveillance.
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HQ: Los Angeles, CA, United States
What they do:
Autonomous offensive security agents. The best defense is offense
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HQ: San Francisco, CA, United States
What they do:
AI-native credentialing and contracting for healthcare
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HQ: New York, NY, United States
What they do:
The BlackRock of collectibles
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HQ: San Francisco, CA, United States
What they do:
Autonomous AI defense system for cyber attack
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HQ: San Francisco, CA, United States
What they do:
OpenRouter for Voice AI: one API, every call on the best speech model
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HQ: San Francisco, CA, United States
What they do:
Building Products and Datasets for Frontier Models
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HQ: San Francisco, CA, United States
What they do:
We turn waste gases into supply-secure chemicals
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HQ: Chicago, IL, United States
What they do:
Nervous System for Physical AI
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HQ: San Francisco, CA, United States
What they do:
Modernizing Chip Manufacturing Infrastructure
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HQ: Ann Arbor, MI, United States
What they do:
Building drone swarms that hunt hidden enemies.
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HQ: San Francisco, CA, United States
What they do:
AI-native procurement services for the physical economy
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HQ: San Francisco, CA, United States
What they do:
Least cost routing system to reduce 70%+ token spend
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HQ: San Francisco, CA, United States
What they do:
Unmanned cargo airplanes
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HQ: Los Angeles, CA, United States
What they do:
Unifying Global Private Credit
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HQ: San Francisco, CA, United States
What they do:
Stripe for medical billing
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HQ: Austin, TX, United States
What they do:
Turn Your Taste Into Hires
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HQ: San Francisco, CA, United States
What they do:
Microgrids in a box built anywhere in days
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HQ: San Francisco, CA, United States
What they do:
Automating away manual admin for food distributors: texts to ERP
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HQ: San Francisco, CA, United States
What they do:
AI agents that run onboarding, adoption, and renewals
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HQ: San Francisco, CA, United States
What they do:
Robots for high skilled labor powering AI infrastructure
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HQ: San Francisco, CA, United States
What they do:
Real-time cloud inference for robotics.
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HQ: San Francisco, CA, United States
What they do:
Shire uses CCTV to run restaurants in real time.
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HQ: Myrtle Beach, SC, United States
What they do:
Enable robots to operate safely in the real world.
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HQ: San Francisco, CA, United States
What they do:
Super fast, unblockable browser infra for agents
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HQ: San Francisco, CA, United States
What they do:
One app for stress-free shopping, cooking, and meal planning.
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HQ: Missoula, MT, United States
What they do:
Push things to your other things.
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HQ: San Francisco, CA, United States
What they do:
Making the JVM faster
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HQ: San Francisco, CA, United States
What they do:
Skyscrape makes temperature-responsive insulation
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HQ: Portland, OR, United States
What they do:
Cutting edge hydrofoil systems for boatbuilders
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HQ: San Francisco, CA, United States
What they do:
Last-mile delivery for perishables.
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HQ: San Francisco, CA, United States
What they do:
Talk & play multiplayer games with your friends!
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HQ: New York, NY, United States
What they do:
YourChoice therapeutics is revolutionizing the contraceptive market…
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HQ: San Francisco, CA, United States