What they do:
Autonomous operations for industrial distributors
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HQ: San Francisco, CA, United States
Top Startups in the United States
This list has 6,379 startups and was last updated on Oct 15, 2026. 1,190 of them are hiring right now. Biggest hubs: San Francisco (3,173), New York (858), and Los Angeles (197). Largest teams: DoorDash, Stripe, and Airbnb. Latest round: Lungpacer Medical raised $7.83M (Oct 14, 2026).
6,379 startupsPage 67 of 178
What they do:
Platform + FDEs that rebuild enterprises agent-first
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HQ: San Francisco, CA, United States
What they do:
Helping your company find 10x engineers.
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HQ: San Francisco, CA, United States
What they do:
AI Back-Office Automation for Commercial Lenders
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HQ: San Francisco, CA, United States
What they do:
Marketplace for AI agents to hire humans.
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HQ: San Francisco, CA, United States
What they do:
Building the Data Infrastructure layer for Physical AI.
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HQ: San Francisco, CA, United States
What they do:
Extrapolative AI to unlock First-in-Class drugs
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HQ: San Francisco, CA, United States
What they do:
AI nutrition coach in your pocket
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HQ: San Francisco, CA, United States
What they do:
The agentic OS for medical labs
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HQ: San Francisco, CA, United States
What they do:
AI-native CRO for clinical trial operations
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HQ: San Francisco, CA, United States
What they do:
Working capital for data companies training frontier AI
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HQ: New York, NY, United States
What they do:
An open-source operating system for reliable long-running agents
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HQ: Boston, MA, United States
What they do:
Simulations of real people for market research
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HQ: San Francisco, CA, United States
What they do:
Patreon for AI Originals
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HQ: San Francisco, CA, United States
What they do:
US stock trading, unlocked for the globe
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HQ: New York, NY, United States
What they do:
AI-native pharma company
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HQ: San Francisco, CA, United States
What they do:
AI-Native FDA Regulatory Services
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HQ: San Francisco, CA, United States
What they do:
Modern Intelligence for Finance
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HQ: New York, NY, United States
What they do:
A personal or team assistant that works while you sleep
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HQ: San Francisco, CA, United States
What they do:
Hickory offers agentic compliance and BSA for banks and fintechs
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HQ: Salt Lake City, UT, United States
What they do:
agents for the rest of us
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HQ: San Francisco, CA, United States
What they do:
We help lawyers start and scale AI-native law firms.
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HQ: San Francisco, CA, United States
What they do:
USA-made magnetics for robotics and defense.
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HQ: Boston, MA, United States
What they do:
The AI-Native Decision Layer for Health Insurance
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HQ: Providence, RI, United States
What they do:
The AI-native contact center
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HQ: San Francisco, CA, United States
What they do:
Watch and create anime
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HQ: San Francisco, CA, United States
What they do:
The market behind AI hardware.
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HQ: San Francisco, CA, United States
What they do:
Building a neutral, sovereign alternative to Starlink
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HQ: San Francisco, CA, United States
What they do:
Making chemicals 100,000x faster
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HQ: San Francisco, CA, United States
What they do:
Reliable and safe data engineering and data science agents
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HQ: San Francisco, CA, United States
What they do:
Build everyday back-office agents on one live model of your books
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HQ: San Francisco, CA, United States
What they do:
Reliable infrastructure to build, deploy and manage real-world robots.
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HQ: Denver, CO, United States
What they do:
Organizing company knowledge
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HQ: San Francisco, CA, United States
What they do:
Infrastructure for building and scaling AI-native businesses.
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HQ: San Francisco, CA, United States
What they do:
AI-native test infrastructure layer for hardware companies
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HQ: San Francisco, CA, United States
What they do:
The social trading app for stocks, memes, and perps
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HQ: San Francisco, CA, United States