What they do:
Airline customer service, fully automated.
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HQ: San Francisco, CA, United States
Top AI Startups in California
This list has 1,429 startups and was last updated on Oct 15, 2026. 461 of them are hiring right now. Biggest hubs: San Francisco (1,355), Los Angeles (47), and San Diego (4). Largest teams: Cruise, Relativity Space, and Athelas. Latest round: Agriculture Scout AI raised $425K (Oct 13, 2026).
1,429 startupsPage 19 of 40
What they do:
Browser infra for AI agents: sessions, auth, proxies, payments
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HQ: San Francisco, CA, United States
What they do:
AI that creates and runs ads, end-end
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HQ: San Francisco, CA, United States
Soren
Hiring
What they do:
The AI Transformation Company
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HQ: San Francisco, CA, United States
YC F25Early stage
What they do:
Adaptive training coach for runners, cyclists, and triathletes
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HQ: San Francisco, CA, United States
What they do:
Trade with superhuman instinct
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HQ: San Francisco, CA, United States
What they do:
AI Infra for real-time vision applications
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HQ: San Francisco, CA, United States
VOYGR
Hiring
What they do:
Real-world place intelligence for AI apps and agents
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HQ: San Francisco, CA, United States
YC W26Early stage
What they do:
Real-world sandboxes to test and train AI agents
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HQ: San Francisco, CA, United States
What they do:
Scale AI scientists whose own breakthroughs accelerate the next.
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HQ: San Francisco, CA, United States
What they do:
The AI-native trading company: factory prices, delivered, one number
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HQ: San Francisco, CA, United States
What they do:
The AI BPO for financial servies, run by computer-use agents
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HQ: San Francisco, CA, United States
What they do:
Earned intelligence for every company
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HQ: San Francisco, CA, United States
What they do:
The company brain for construction companies
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HQ: San Francisco, CA, United States
What they do:
AI that finds value creation opportunities across enterprise…
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HQ: San Francisco, CA, United States
Operon
Hiring
What they do:
Agentic data layer for manufacturing & process industries.
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HQ: San Francisco, CA, United States
YC S26Early stage
Lamb Labs
Hiring
What they do:
Lightning fast chips with hardcoded AI models
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HQ: San Francisco, CA, United States
YC S26Early stage
What they do:
Context layer for enterprise AI surveying employees with voice agents
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HQ: San Francisco, CA, United States
What they do:
We tell sellers exactly when a company is ready to buy.
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HQ: San Francisco, CA, United States
What they do:
A live watermark inside AI voice that survives phone calls
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HQ: San Francisco, CA, United States
What they do:
Synvivia applies chemical control over cell behavior
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HQ: San Francisco, CA, United States
What they do:
Shiru leverages ML to create proteins to feed the world sustainably.
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HQ: San Francisco, CA, United States
What they do:
AI-Native Restaurant POS
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HQ: San Francisco, CA, United States
What they do:
Developing milk-inspired therapeutics for infectious diseases
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HQ: Davis, CA, United States
What they do:
Classify Anything
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HQ: CA, United States
What they do:
We make it simple for call centers to automate quality assurance.
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HQ: San Francisco, CA, United States
What they do:
AI agents rewriting & optimising your internal documentation for LLMs
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HQ: San Francisco, CA, United States
What they do:
Get your brand discovered and recommended by ChatGPT
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HQ: San Francisco, CA, United States
What they do:
Building the definitive all-in-one on-device AI productivity tool
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HQ: Los Angeles, CA, United States
What they do:
Superpowers for litigators
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HQ: San Francisco, CA, United States
What they do:
AI-powered product assistance for modern software teams
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HQ: San Francisco, CA, United States
What they do:
Read romance comics.
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HQ: San Francisco, CA, United States
What they do:
Frontier AI to stop fraud, abuse, and financial crimes.
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HQ: San Francisco, CA, United States
What they do:
The spatial AI to plan, build and maintain the world's infrastructure
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HQ: San Francisco, CA, United States
What they do:
An AI tutor that helps you study
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HQ: San Francisco, CA, United States
What they do:
Automating Data Entry for Clinical Trials
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HQ: San Francisco, CA, United States