What they do:
Using CRISPR to find treatments for cancer and inflammation
Quick facts:
HQ: San Francisco, CA, United States
Top AI Startups in California
This list has 1,429 startups and was last updated on Oct 15, 2026. 461 of them are hiring right now. Biggest hubs: San Francisco (1,355), Los Angeles (47), and San Diego (4). Largest teams: Cruise, Relativity Space, and Athelas. Latest round: Agriculture Scout AI raised $425K (Oct 13, 2026).
1,429 startupsPage 7 of 40
What they do:
Affogato AI — Your Agent for instant TikToks, Reels, and ads.
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HQ: San Francisco, CA, United States
What they do:
AI SDET for mobile apps
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HQ: San Francisco, CA, United States
Dart
Hiring
What they do:
The work and agent management platform
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HQ: San Francisco, CA, United States
Julius
Hiring
What they do:
Build and analyze things with AI
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HQ: San Francisco, CA, United States
Coris
Hiring
What they do:
AI risk and ops platform for Payment Processors, Banks, SaaS…
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HQ: San Francisco, CA, United States
Rubbrband
Hiring
What they do:
A new kind of creative company.
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HQ: San Francisco, CA, United States
Reflex
Hiring
What they do:
The operating system for building mission-critical enterprise apps.
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HQ: San Francisco, CA, United States
What they do:
Social listening for the video era
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HQ: San Francisco, CA, United States
Magic Patterns
Hiring
What they do:
Go from idea to production with AI.
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HQ: San Francisco, CA, United States
What they do:
Automating Healthcare Revenue Cycle Management with AI Workforce
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HQ: San Francisco, CA, United States
Diffuse Bio
Hiring
What they do:
Generative AI for protein design
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HQ: San Francisco, CA, United States
What they do:
AI Agents For RFP and Questionnaire Response Automation
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HQ: San Francisco, CA, United States
Event Horizon Labs
Hiring
What they do:
AI research lab automating all of investing
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HQ: San Francisco, CA, United States
Zep AI
Hiring
What they do:
The unified context layer for enterprise data
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HQ: San Francisco, CA, United States
TrueClaim
Hiring
What they do:
Transparent, AI-powered healthcare TPA.
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HQ: San Francisco, CA, United States
Coval
Hiring
What they do:
Simulation & Evaluation that scales voice and chat AI agents
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HQ: San Francisco, CA, United States
Mem0
Hiring
What they do:
The Memory layer for AI Agents
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HQ: San Francisco, CA, United States
David AI
Hiring
What they do:
Data for audio AI
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HQ: San Francisco, CA, United States
Thunder Compute
Hiring
What they do:
GPUs for Agents
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HQ: San Francisco, CA, United States
Syntra
Hiring
What they do:
Faster healthcare payments
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HQ: San Francisco, CA, United States
CTGT
Hiring
What they do:
The deterministic layer for frontier intelligence
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HQ: San Francisco, CA, United States
Proception Inc
Hiring
What they do:
Making humanoids dexterous enough to thread a needle
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HQ: San Francisco, CA, United States
Sim
Hiring
What they do:
Build autonomous AI agents for enterprise systems
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HQ: San Francisco, CA, United States
Bluejay
Hiring
What they do:
Test, monitor, and improve your voice and chat AI agents
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HQ: San Francisco, CA, United States
QualGent
Hiring
What they do:
AI Mobile App Quality Assurance Tester
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HQ: San Francisco, CA, United States
Besimple AI
Hiring
What they do:
Voice data for AI
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HQ: San Francisco, CA, United States
Vesence
Hiring
What they do:
AI for High-Stakes Work
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HQ: San Francisco, CA, United States
Godela
Hiring
What they do:
AI Physics Engine to replace simulations and prototypes
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HQ: San Francisco, CA, United States
What they do:
AI that makes AI fast
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HQ: San Francisco, CA, United States
Reacher
Hiring
What they do:
We automate creator marketing for the world's largest brands
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HQ: San Francisco, CA, United States
Veritus
Hiring
What they do:
AI agents for the consumer lending industry
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HQ: San Francisco, CA, United States
What they do:
AI Operating System for Legal Teams
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HQ: San Francisco, CA, United States
Lance
Hiring
What they do:
AI Agents That Run Hotel Operations.
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HQ: San Francisco, CA, United States
BioStack Platforms
Hiring
What they do:
Real world training envs for healthcare AI models
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HQ: San Francisco, CA, United States
iSono Health
Hiring
What they do:
AI-powered platform for Accessible and Personalized Breast Health…
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HQ: San Francisco, CA, United States