Quick facts:
HQ: Boston, MA, United States
Incorporated: 2025
Funding:
$25M · Equity · Feb 2026
Top Biotech Startups in Massachusetts
This list has 66 startups and was last updated on Oct 15, 2026. 5 of them are hiring right now. Biggest hubs: Boston (35), Cambridge (7), and Waltham (3). Largest teams: Ginkgo Bioworks, OpenBiome, and Volta Labs, Inc. Latest round: Axelyf raised $2.63M (Oct 13, 2026).
66 startupsPage 2 of 2
Quick facts:
HQ: Cambridge, MA, United States
Funding:
$25M · Equity · Mar 2026
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HQ: Watertown, MA, United States
Funding:
$23M · Equity · Mar 2026
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HQ: Cambridge, MA, United States
Incorporated: 2024
Funding:
$22.5M · SAFE · Mar 2026
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HQ: Hudson, MA, United States
Funding:
$20M · Equity + debt · Apr 2026
Quick facts:
HQ: Boston, MA, United States
Funding:
$17.3M · Equity · May 2026
Quick facts:
HQ: Boston, MA, United States
Incorporated: 2026
Funding:
$14M · Equity · May 2026
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HQ: Newton, MA, United States
Funding:
$13.2M · Equity · May 2026
Quick facts:
HQ: Cambridge, MA, United States
Incorporated: 2025
Funding:
$10M · Equity · Jun 2026
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HQ: Watertown, MA, United States
Incorporated: 2021
Funding:
$10M · Equity · Jun 2026
Quick facts:
HQ: Boston, MA, United States
Incorporated: 2024
Funding:
$10M · Equity · Mar 2026
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HQ: Arlington, MA, United States
Incorporated: 2022
Funding:
$9M · Equity · May 2026
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HQ: Billerica, MA, United States
Funding:
$6.7M · Equity · Jun 2026
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HQ: Cambridge, MA, United States
Funding:
$5M · Equity · May 2026
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HQ: Newton, MA, United States
Funding:
$4.81M · SAFE · Apr 2026
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HQ: Somerville, MA, United States
Incorporated: 2025
Funding:
$4.5M · Equity · Feb 2026
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HQ: Waltham, MA, United States
Incorporated: 2024
Funding:
$4.35M · Equity · Mar 2026
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HQ: Dedham, MA, United States
Funding:
$3.95M · Debt · Jun 2026
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HQ: Worcester, MA, United States
Incorporated: 2021
Funding:
$3.16M · Equity + debt · Mar 2026
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HQ: Chestnut Hill, MA, United States
Incorporated: 2025
Funding:
$2.63M · Equity · Oct 2026
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HQ: Lowell, MA, United States
Incorporated: 2024
Funding:
$2.33M · Equity · Apr 2026
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HQ: Arlington, MA, United States
Funding:
$1.75M · Equity · Mar 2026
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HQ: Needham, MA, United States
Funding:
$1.5M · Equity · May 2026
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HQ: Arlington, MA, United States
Incorporated: 2026
Funding:
$1.3M · SAFE · Jun 2026
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HQ: Mansfield, MA, United States
Funding:
$1.2M · Debt · Oct 2026
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HQ: Framingham, MA, United States
Funding:
$1M · Equity · Apr 2026
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HQ: Pembroke, MA, United States
Funding:
$681K · Equity · Oct 2026
One Codex
Acquired
What they do:
Data platform for metagenomics and the microbiome.
Quick facts:
HQ: Boston, MA, United States
Reverie Labs
Shut down
What they do:
Engineering next-generation, brain-penetrant cancer therapies.
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HQ: Boston, MA, United States
Radix Labs
Shut down
What they do:
Operating systems for biology labs
Quick facts:
HQ: Boston, MA, United States