What they do:
Agents for Accelerated Clinical Trial Design
Quick facts:
HQ: Boston, MA, United States
Top Biotech Startups in the United States
This list has 451 startups and was last updated on Oct 15, 2026. 34 of them are hiring right now. Biggest hubs: San Francisco (134), Boston (35), and New York (27). Largest teams: Benchling, Ginkgo Bioworks, and BillionToOne. Latest round: Renue Life Sciences raised $250K (Oct 14, 2026).
451 startupsPage 2 of 13
Nest Genomics
Hiring
What they do:
Software to launch and integrate genetics into clinical care
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HQ: New York, NY, United States
What they do:
Fermentation-derived natural products to solve health problems
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HQ: San Diego, CA, United States
Andson Biotech
Hiring
What they do:
Empowering Mass Spec for Biotech and Beyond
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HQ: Atlanta, GA, United States
What they do:
Discovering drugs that target the DNA regulome
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HQ: Seattle, WA, United States
Data Driven Bioscience
Hiring
What they do:
Cancer Diagnosis 10X faster, 10X cheaper
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HQ: Durham, NC, United States
What they do:
Using CRISPR to find treatments for cancer and inflammation
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HQ: San Francisco, CA, United States
What they do:
Gilgamesh Pharmaceuticals, a Clinical stage biotechnology company…
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HQ: New York, NY, United States
What they do:
Discovering bispecific antibody drug-conjugates (BsADC) against cancer
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HQ: Boston, MA, United States
What they do:
DNA App Store
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HQ: San Francisco, CA, United States
Diffuse Bio
Hiring
What they do:
Generative AI for protein design
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HQ: San Francisco, CA, United States
Maven Bio
Hiring
What they do:
Live intelligence for biopharma teams.
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HQ: Boston, MA, United States
What they do:
Computational antibody design
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HQ: Austin, TX, United States
What they do:
FidoCure® is the leader in Precision Medicine for Canine Oncology.
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HQ: San Francisco, CA, United States
What they do:
We create activating antibodies to treat diseases others can’t.
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HQ: San Francisco, CA, United States
SafeBeat
Hiring
What they do:
First ECG AI to go beyond diagnostics and recommend treatment
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HQ: San Francisco, CA, United States
Pirouette Pharma
Hiring
What they do:
We make injections as easy as pushing a button!
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HQ: Boston, MA, United States
What they do:
Cofactor closes the precision medicine gap with predictive diagnostics
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HQ: St. Louis, MO, United States
Biodock
Hiring
What they do:
Cloud AI microscopy automation
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HQ: Austin, TX, United States
Epinoma
Hiring
What they do:
We engineer proteins that control the operating system of biology.
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HQ: San Francisco, CA, United States
Output Labs
Hiring
What they do:
The foundation for the next era of science
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HQ: New York, NY, United States
Origin
Hiring
What they do:
AI and Data for Cancer Therapeutics
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HQ: San Francisco, CA, United States
What they do:
We design and build microbes to make chemicals greener at lower cost.
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HQ: San Francisco, CA, United States
What they do:
We bank your stem cells to help you live healthier, longer.
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HQ: Ann Arbor, MI, United States
What they do:
Rebellyous Foods is a food manufacturing technology and production…
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HQ: Seattle, WA, United States
What they do:
The free HIV vaccine.
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HQ: San Francisco, CA, United States
What they do:
Finding the right cancer drug for each patient.
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HQ: Walnut, CA, United States
Raycaster
Hiring
What they do:
Agentic AI for knowledge work
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HQ: New York, NY, United States
What they do:
Patent-pending enzymes to break down common dietary triggers
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HQ: Boston, MA, United States
What they do:
We recycle plastic using engineered enzymes
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HQ: Portland, OR, United States
10x Science
Hiring
What they do:
The AI-native platform for next-generation protein characterization.
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HQ: San Francisco, CA, United States
CellType
Hiring
What they do:
The agentic drug company. We simulate human biology.
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HQ: New York, NY, United States
What they do:
Human whole body end-of-life preservation for later revival.
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HQ: Portland, OR, United States
What they do:
We use AI to design antibodies for intractable diseases
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HQ: Boston, MA, United States
What they do:
Multi-targeted therapeutics to treat complex diseases
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HQ: New York, NY, United States
GloGlo
Hiring
What they do:
Curing and preventing type 1 diabetes
Quick facts:
HQ: San Francisco, CA, United States