Marble
Hiring
What they do:
The autonomous back-of-house for restaurants.
Quick facts:
HQ: New York, NY, United States
Top Deep Tech Startups in New York State
This list has 150 startups and was last updated on Oct 15, 2026. 51 of them are hiring right now. Biggest hubs: New York (137), Brooklyn (5), and Albany (2). Largest teams: Nabis, Guesty, and Odeko. Latest round: Enthos Circular Feed Technologies raised $8M (Oct 14, 2026).
150 startupsPage 3 of 5
AptDeco
Hiring
What they do:
AptDeco is the easiest way to buy and sell used furniture
Quick facts:
HQ: New York, NY, United States
YC W14Growth stage
What they do:
"Name Your Price" for products
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HQ: New York, NY, United States
What they do:
Sourcing investment real estate
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HQ: New York, NY, United States
What they do:
A platform to make artificial viruses as cancer therapeutics.
Quick facts:
HQ: New York, NY, United States
What they do:
Empowering every doctor and every patient to participate in research
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HQ: New York, NY, United States
IronLedger.ai
Hiring
What they do:
AI-enabled Corporate Cards and Invoice Processing for Real Estate
Quick facts:
HQ: New York, NY, United States
YC S25Early stage
What they do:
Find culinary products and experiences from great makers everywhere
Quick facts:
HQ: New York, NY, United States
What they do:
Next-generation biocides for sustainable agriculture at scale
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HQ: New York, NY, United States
What they do:
Optimize performance on GPUs - 10x faster
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HQ: New York, NY, United States
What they do:
An AI-powered test and debug platform for chip developers
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HQ: New York, NY, United States
What they do:
AI teammate for finance and operations teams at consumer brands
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HQ: New York, NY, United States
What they do:
The reliability platform for last-mile delivery
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HQ: New York, NY, United States
What they do:
AI infrastructure for biosecurity
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HQ: New York, NY, United States
What they do:
The AI equipment manager for post-acute care
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HQ: New York, NY, United States
What they do:
Smarter Spending for Vacation Property Managers
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HQ: New York, NY, United States
What they do:
Platform for cities to optimize transit
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HQ: New York, NY, United States
What they do:
Build full-stack applications for business operations with AI
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HQ: New York, NY, United States
What they do:
AI Compliance for Affordable Housing
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HQ: New York, NY, United States
What they do:
Valuemate automates real estate appraisals with AI
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HQ: New York, NY, United States
What they do:
AI Takeoffs for Electrical
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HQ: New York, NY, United States
What they do:
Next generation robot deployer
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HQ: New York, NY, United States
What they do:
Automatic Construction Drawing Clash Detection
Quick facts:
HQ: New York, NY, United States
What they do:
Making Defense Manufacturing Faster and Cheaper
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HQ: New York, NY, United States
What they do:
The operating system for commercial buildings.
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HQ: Niagara Falls, NY, United States
What they do:
Power-ready land for AI data centers
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HQ: New York, NY, United States
What they do:
Find a home you can actually afford
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HQ: New York, NY, United States
YC W22Early stage
What they do:
Fixing air traffic control with remote towers
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HQ: New York, NY, United States
YC X26Early stage
What they do:
World Model for Freight
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HQ: New York, NY, United States
YC S26Early stage
Quick facts:
HQ: Batavia, NY, United States
Funding:
$50M · Equity · Apr 2026
Quick facts:
HQ: New York, NY, United States
Funding:
$20M · Equity · Mar 2026
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HQ: Buffalo, NY, United States
Funding:
$20M · Debt · Feb 2026
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HQ: Brooklyn, NY, United States
Funding:
$10.1M · Equity · Jan 2026
Quick facts:
HQ: New York, NY, United States
Incorporated: 2025
Funding:
$9.85M · Equity · Feb 2026
Quick facts:
HQ: New York, NY, United States
Incorporated: 2021
Funding:
$8M · Debt · Oct 2026
Quick facts:
HQ: Brooklyn, NY, United States
Incorporated: 2024
Funding:
$5.35M · Equity · May 2026