What they do:
Motor cortex for physical AI
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HQ: San Francisco, CA, United States
Top Deep Tech Startups in San Francisco
This list has 704 startups and was last updated on Oct 15, 2026. 180 of them are hiring right now. Largest teams: DoorDash, GrubMarket, and Instacart. Latest round: Aikido Technologies raised $1.72M (Oct 8, 2026).
704 startupsPage 11 of 20
What they do:
100% automated inspection for consumer electronics parts
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HQ: San Francisco, CA, United States
What they do:
Online circuit simulator and electronic schematic editor.
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HQ: San Francisco, CA, United States
What they do:
Fastest, easiest, and most affordable way for small business owners…
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HQ: San Francisco, CA, United States
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Synkrino's AI, SATIS is a powerful, unbiased discovery system for…
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HQ: San Francisco, CA, United States
What they do:
We put farms inside restaurants, so customers get healthier food and…
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HQ: San Francisco, CA, United States
What they do:
The Self-Hosting Company
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HQ: San Francisco, CA, United States
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Menten AI designs peptide and protein therapeutics using quantum…
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HQ: San Francisco, CA, United States
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Neurostimulation implant to restore hearing & speech understanding
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HQ: San Francisco, CA, United States
What they do:
Automated phone ordering system for restaurants
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HQ: San Francisco, CA, United States
What they do:
Growing seaweed to stabilize the climate.
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HQ: San Francisco, CA, United States
What they do:
Single source of truth for your clinic's finances and supply chain.
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HQ: San Francisco, CA, United States
What they do:
Automating nutrition tracking.
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HQ: San Francisco, CA, United States
What they do:
Genetically engineering plants for disease resistance.
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HQ: San Francisco, CA, United States
What they do:
AI agents to enroll providers with payors
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HQ: San Francisco, CA, United States
What they do:
AI agent for construction drawings review
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HQ: San Francisco, CA, United States
What they do:
Datadog for robots
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HQ: San Francisco, CA, United States
What they do:
Propaya is an AI-powered commercial real estate intelligence platform that transforms leases and property documents into structured, actionable data. It…
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HQ: San Francisco, CA, United States
What they do:
Autonomous intake and RCM for specialty clinics.
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HQ: San Francisco, CA, United States
What they do:
Making procurement easy
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HQ: San Francisco, CA, United States
What they do:
Your AI scheduling assistant for construction
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HQ: San Francisco, CA, United States
What they do:
AI-native remote operations center for hardware fleets
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HQ: San Francisco, CA, United States
What they do:
AI personal assistant for in-home sales
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HQ: San Francisco, CA, United States
What they do:
All-In-One AI Growth Partner. Built for Trades.
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HQ: San Francisco, CA, United States
What they do:
Physics-based foundation models for CAD optimization.
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HQ: San Francisco, CA, United States
What they do:
End-to-end Simulation for Defense Autonomy
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HQ: San Francisco, CA, United States
What they do:
Self learning computer use agent for developers
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HQ: San Francisco, CA, United States
What they do:
Building intellectually curious AI
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HQ: San Francisco, CA, United States
What they do:
Building tiny frontier AI models that run on edge devices
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HQ: San Francisco, CA, United States
What they do:
AI-Native Data Center Engineering
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HQ: San Francisco, CA, United States
What they do:
The Cursor for Chip Design - Delivering Silicon-Ready Chip Designs…
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HQ: San Francisco, CA, United States
What they do:
Waymo for excavators
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HQ: San Francisco, CA, United States
What they do:
AI-native ERP for manufacturers
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HQ: San Francisco, CA, United States
What they do:
Delivering AI-powered situational awareness in tactical environments.
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HQ: San Francisco, CA, United States
What they do:
Fast Physics Simulations for Rapid Design and Real Time Control
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HQ: San Francisco, CA, United States
What they do:
Autonomous OS for healthcare
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HQ: San Francisco, CA, United States