What they do:
Tankless Dive Gear - Breath Autonomy at Sea, Land & Space
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HQ: San Francisco, CA, United States
Top Deep Tech Startups in the United States
This list has 1,386 startups and was last updated on Oct 15, 2026. 306 of them are hiring right now. Biggest hubs: San Francisco (704), New York (137), and Los Angeles (79). Largest teams: DoorDash, EquipmentShare, and GrubMarket. Latest round: Onebrief raised $151M (Oct 14, 2026).
1,386 startupsPage 23 of 39
What they do:
AI agent that manages manufacturing operations over text
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HQ: San Francisco, CA, United States
What they do:
Camera-free AI glasses. Your AI, out in the world.
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HQ: San Francisco, CA, United States
What they do:
Robots to maintain and assemble data centers
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HQ: San Francisco, CA, United States
What they do:
Vaccines for any cancer or infection in weeks.
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HQ: San Francisco, CA, United States
What they do:
Force-sensing wristband for training robotic AI
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HQ: San Francisco, CA, United States
What they do:
Actuators for Physical AI
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HQ: San Francisco, CA, United States
What they do:
Android for drones
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HQ: San Francisco, CA, United States
What they do:
We help retailers and restaurant chains manage repairs and…
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HQ: San Francisco, CA, United States
YC S18Early stage
What they do:
24/7 emergency maintenance department for property managers and…
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HQ: Seattle, WA, United States
What they do:
Eclipse Foods is building the future of dairy using micelles, the…
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HQ: San Francisco, CA, United States
YC W19Growth stage
What they do:
Next-Generation Surgical Navigation and Robotics
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HQ: Boston, MA, United States
YC S19Early stage
What they do:
Avion builds and operates autonomous eVTOL drones that deliver vital…
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HQ: San Francisco, CA, United States
YC W20Early stage
What they do:
AI copilot for real-estate sales teams, powered by proprietary data
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HQ: Saint Petersburg, FL, United States
YC W22Early stage
What they do:
Find a home you can actually afford
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HQ: New York, NY, United States
YC W22Early stage
What they do:
Transform Images And Videos Into Immersive 3D With AI
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HQ: San Francisco, CA, United States
YC S24Early stage
What they do:
Accelerating world models.
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HQ: San Francisco, CA, United States
YC X25Early stage
What they do:
General Purpose Robots
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HQ: San Francisco, CA, United States
YC F25Early stage
What they do:
AI-controlled optical switching for AI clusters
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HQ: Boston, MA, United States
YC S26Early stage
What they do:
AI Employee for Manufacturing Operations
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HQ: San Francisco, CA, United States
YC X26Early stage
What they do:
Fixing air traffic control with remote towers
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HQ: New York, NY, United States
YC X26Early stage
What they do:
We make the most compact nuclear reactors
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HQ: Boston, MA, United States
YC X26Early stage
What they do:
We help Fortune 500 companies hedge their supply chain risk
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HQ: San Francisco, CA, United States
YC S26Early stage
What they do:
Teaching AI to Design Chips
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HQ: San Francisco, CA, United States
YC S26Early stage
What they do:
Autonomous Hardware Testing
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HQ: San Francisco, CA, United States
YC S26Early stage
What they do:
World Model for Freight
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HQ: New York, NY, United States
YC S26Early stage
What they do:
Autopilot for Flight Operations
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HQ: San Francisco, CA, United States
YC S26Early stage
What they do:
Hyperscaling space manufacturing
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HQ: Los Angeles, CA, United States
YC F26Early stage
What they do:
Autonomous CNC factories for faster hardware
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HQ: San Francisco, CA, United States
YC F26Early stage
What they do:
Resin helps engineers design electronics faster and more reliably
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HQ: San Francisco, CA, United States
YC F26Early stage
What they do:
AI-guided ballistic missiles, cheap enough to field in numbers that…
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HQ: San Francisco, CA, United States
YC F26Early stage
Cruise
Acquired
What they do:
Self-driving cars.
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HQ: San Francisco, CA, United States
PlanGrid
Acquired
What they do:
Mobile applications for the construction industry.
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HQ: San Francisco, CA, United States
Quick facts:
HQ: Washington, DC, United States
Incorporated: 2025
Funding:
$250M · Equity + debt · Jan 2026
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HQ: El Segundo, CA, United States
Incorporated: 2024
Funding:
$245M · Equity · May 2026
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HQ: Boston, MA, United States
Funding:
$180M · Equity · Apr 2026