SiPhox Health
Hiring
What they do:
At-Home health monitoring with silicon photonic chips for data centers
Quick facts:
HQ: Boston, MA, United States
Top Deep Tech Startups in the United States
This list has 1,386 startups and was last updated on Oct 15, 2026. 306 of them are hiring right now. Biggest hubs: San Francisco (704), New York (137), and Los Angeles (79). Largest teams: DoorDash, EquipmentShare, and GrubMarket. Latest round: Onebrief raised $151M (Oct 14, 2026).
1,386 startupsPage 3 of 39
What they do:
Workforce Management for Large Farms
Quick facts:
HQ: Los Angeles, CA, United States
Ready
Hiring
What they do:
Collaborative platform for optimizing regulated utilities such as…
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HQ: San Francisco, CA, United States
Atomic Industries
Hiring
What they do:
Software orchestrated mass production of plastics
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HQ: Cleveland, OH, United States
Shepherd
Hiring
What they do:
Modernizing commercial insurance
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HQ: San Francisco, CA, United States
Cambio
Hiring
What they do:
AI-native commercial real estate operations
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HQ: San Francisco, CA, United States
What they do:
Home boxing gym with motion trackers that compute punches and reps.
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HQ: Los Angeles, CA, United States
Quindar
Hiring
What they do:
Datadog for Space
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HQ: Denver, CO, United States
What they do:
We verify global supply chains for issues like child slavery and…
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HQ: New York, NY, United States
Albedo
Hiring
What they do:
Full-stack VLEO satellite missions
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HQ: Denver, CO, United States
What they do:
Plug-and-play AI platform with sensors and dashboards that makes…
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HQ: Atlanta, GA, United States
What they do:
Cheese and dairy products from plant-derived dairy proteins
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HQ: San Francisco, CA, United States
What they do:
The lightest electric aircraft motors in the world.
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HQ: Denver, CO, United States
Glimpse
Hiring
What they do:
Glimpse is the system of action for CPG retail operations
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HQ: New York, NY, United States
Astro Mechanica
Hiring
What they do:
Supersonics for the new Jet Age
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HQ: San Francisco, CA, United States
Nox Metals
Hiring
What they do:
Supplying America's Industrial Base
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HQ: Detroit, MI, United States
Lugg
Hiring
What they do:
Move anything, anytime, anywhere
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HQ: Salt Lake City, UT, United States
Verge Genomics
Hiring
What they do:
We use human data and AI to develop better drugs faster.
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HQ: San Francisco, CA, United States
What they do:
Lygos (W16) built and commercialized sustainable, high-performance…
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HQ: San Francisco, CA, United States
Volta Labs, Inc.
Hiring
What they do:
Unlocking the utility of genomics for the world.
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HQ: Boston, MA, United States
LineLeap
Hiring
What they do:
LineLeap gets customers to the fun, faster.
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HQ: New York, NY, United States
Soraban
Hiring
What they do:
AI tax workflow platform for accounting firms
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HQ: Tempe, AZ, United States
Agave
Hiring
What they do:
Applied AI for Construction
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HQ: San Francisco, CA, United States
Craftwork
Hiring
What they do:
Digital-native home painting franchise
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HQ: Charlotte, NC, United States
Icarus
Hiring
What they do:
Stratospheric birds for defense
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HQ: Los Angeles, CA, United States
Paces
Hiring
What they do:
Agentic AI for Power Projects and AI Infrastructure
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HQ: New York, NY, United States
What they do:
The shipping infrastructure of the internet.
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HQ: Austin, TX, United States
What they do:
Petcube is on the mission to improve lives of pets and pet owners…
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HQ: San Francisco, CA, United States
Reach
Hiring
What they do:
Long range, wireless energy distribution that scales
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HQ: San Francisco, CA, United States
What they do:
Heart makes electric airplanes with an all-electric range of 250 miles
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HQ: Los Angeles, CA, United States
What they do:
Enterprise software to quantify cost-effective decarbonization…
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HQ: San Francisco, CA, United States
What they do:
Bluetooth to Space
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HQ: Las Vegas, NV, United States
What they do:
Fetii is an AI-driven mobility platform
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HQ: Austin, TX, United States
What they do:
Premier growth platform for restaurants
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HQ: Lehi, UT, United States
What they do:
Building robotic mushroom farms
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HQ: San Francisco, CA, United States
What they do:
The operating system powering ecommerce fulfillment
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HQ: Los Angeles, CA, United States