What they do:
Frozen beauty products.
Quick facts:
HQ: Philadelphia, PA, United States
Top Deep Tech Startups in the United States
This list has 1,386 startups and was last updated on Oct 15, 2026. 306 of them are hiring right now. Biggest hubs: San Francisco (704), New York (137), and Los Angeles (79). Largest teams: DoorDash, EquipmentShare, and GrubMarket. Latest round: Onebrief raised $151M (Oct 14, 2026).
1,386 startupsPage 7 of 39
Farcast
Hiring
What they do:
We build advanced satcom user terminals
Quick facts:
HQ: San Francisco, CA, United States
Andson Biotech
Hiring
What they do:
Empowering Mass Spec for Biotech and Beyond
Quick facts:
HQ: Atlanta, GA, United States
inBuild
Hiring
What they do:
Workflow Automation for Construction Finance
Quick facts:
HQ: Wilmington, DE, United States
Andromeda Surgical
Hiring
What they do:
Autonomous surgical robots
Quick facts:
HQ: San Francisco, CA, United States
RetailReady
Hiring
What they do:
An AI-powered supply chain compliance engine
Quick facts:
HQ: San Francisco, CA, United States
Drillbit
Hiring
What they do:
Automating Office Work for Residential Contractors.
Quick facts:
HQ: Austin, TX, United States
Cartage
Hiring
What they do:
Autonomous freight coordination
Quick facts:
HQ: San Francisco, CA, United States
Starcloud
Hiring
What they do:
Data centers in space
Quick facts:
HQ: Seattle, WA, United States
Assembly HOA
Hiring
What they do:
AI-native HOA Management Company
Quick facts:
HQ: San Francisco, CA, United States
Reditus Space
Hiring
What they do:
Reusable Satellites
Quick facts:
HQ: Atlanta, GA, United States
What they do:
Discovering drugs that target the DNA regulome
Quick facts:
HQ: Seattle, WA, United States
Odys Aviation
Hiring
What they do:
Vertical takeoff and landing aircraft for major airlines
Quick facts:
HQ: Los Angeles, CA, United States
What they do:
Nuclear-inspired cooling that turns wasted power into more AI compute
Quick facts:
HQ: San Francisco, CA, United States
AirMyne
Hiring
What they do:
Building systems to remove carbon dioxide from air at industrial scale
Quick facts:
HQ: San Francisco, CA, United States
Lanesurf
Hiring
What they do:
Book any load in 10 minutes
Quick facts:
HQ: San Francisco, CA, United States
Fleetline
Hiring
What they do:
Optimizing fleet planning with data driven algorithms
Quick facts:
HQ: New York, NY, United States
Structured AI
Hiring
What they do:
The AI drawing review platform for architects and engineers.
Quick facts:
HQ: New York, NY, United States
What they do:
Curtsy is a sustainable clothing resale app.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Great tasting produce, farmed around the corner
Quick facts:
HQ: Washington, DC, United States
Vorticity
Hiring
What they do:
The Fastest Scientific Computing Platform on the Planet
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Route Optimisation platform for SMB in delivery & home services.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Using CRISPR to find treatments for cancer and inflammation
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Gilgamesh Pharmaceuticals, a Clinical stage biotechnology company…
Quick facts:
HQ: New York, NY, United States
Fractional
Hiring
What they do:
The place where motivated investors and entrepreneurs co-own together.
Quick facts:
HQ: San Francisco, CA, United States
AstroForge
Hiring
What they do:
We Mine Asteroids
Quick facts:
HQ: Los Angeles, CA, United States
Posh
Hiring
What they do:
Rapidly deployable energy solutions for modern commercial and…
Quick facts:
HQ: San Francisco, CA, United States
Olympian Motors
Hiring
What they do:
Next-generation, modular electric vehicles
Quick facts:
HQ: New York, NY, United States
What they do:
We make plant-based steaks with an authentic texture
Quick facts:
HQ: New York, NY, United States
Tank Payments
Hiring
What they do:
Modern financial infrastructure for the trucking industry.
Quick facts:
HQ: Austin, TX, United States
What they do:
Code-first scrapers and RPAs — built and maintained by AI
Quick facts:
HQ: Seattle, WA, United States
What they do:
Bluedot is a single payment platform for EV drivers and fleets.
Quick facts:
HQ: San Francisco, CA, United States
Diffuse Bio
Hiring
What they do:
Generative AI for protein design
Quick facts:
HQ: San Francisco, CA, United States
Airgoods
Hiring
What they do:
The modern distributor for grocers.
Quick facts:
HQ: New York, NY, United States
Offstream
Hiring
What they do:
Vanta for carbon compliance
Quick facts:
HQ: Denver, CO, United States
Pax
Hiring
What they do:
AI Broker for Tariff Refunds
Quick facts:
HQ: San Francisco, CA, United States