
What they do:
AI for the physical world
Quick facts:
HQ: San Francisco, CA, United States
This list has 1,861 startups and was last updated on Oct 15, 2026. 377 of them are hiring right now. Biggest hubs: San Francisco (704), New York (137), and Los Angeles (79). Largest teams: Breadfast, DoorDash, and EquipmentShare. Latest round: Scimplify raised $25M (Oct 15, 2026).
Survival statistics →1,040 open roles →

What they do:
AI for the physical world
Quick facts:
HQ: San Francisco, CA, United States

What they do:
Truckload Planning at Machine Precision
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HQ: San Francisco, CA, United States

What they do:
AI-native real estate services firm
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HQ: Los Angeles, CA, United States

What they do:
AI-native software for managing rail and bulk operations.
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HQ: Olathe, KS, United States

What they do:
Digital transformation for real economy businesses
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HQ: San Francisco, CA, United States

What they do:
The AI equipment manager for post-acute care
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HQ: New York, NY, United States

What they do:
Frontier grows scalable biological brains as an ML training substrate
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HQ: London, United Kingdom

What they do:
Large-scale real-world robot & human data for embodied AI
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HQ: San Francisco, CA, United States

What they do:
Machine intelligence for American Welding
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HQ: Los Angeles, CA, United States

What they do:
Vanta for hardware
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HQ: San Francisco, CA, United States

What they do:
Technology to detect and track small drones
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HQ: London, United Kingdom

What they do:
Energy independent data centers with solar and repurposed batteries.
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What they do:
Software for enterprise energy procurement.
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What they do:
Autonomous operations for industrial distributors
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HQ: San Francisco, CA, United States

What they do:
AI-automated factory for PCBAs
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What they do:
Measure freight with security cameras
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What they do:
AI mobile app that helps factory technicians fix broken machines
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HQ: Germany

What they do:
Building the Data Infrastructure layer for Physical AI.
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HQ: San Francisco, CA, United States

What they do:
AI agents that interviews every employee to hand context to AI tools.
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What they do:
AI-native pharma company
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HQ: San Francisco, CA, United States

What they do:
USA-made magnetics for robotics and defense.
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HQ: Boston, MA, United States

What they do:
The market behind AI hardware.
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HQ: San Francisco, CA, United States

What they do:
Building a neutral, sovereign alternative to Starlink
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HQ: San Francisco, CA, United States

What they do:
Making chemicals 100,000x faster
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HQ: San Francisco, CA, United States

What they do:
Reliable infrastructure to build, deploy and manage real-world robots.
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HQ: Denver, CO, United States

What they do:
AI-native test infrastructure layer for hardware companies
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HQ: San Francisco, CA, United States

What they do:
Agentic procurement & inventory for deep tech teams.
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What they do:
Turns real businesses into robotics data vendors
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HQ: San Francisco, CA, United States

What they do:
Evals for robots
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HQ: San Francisco, CA, United States

What they do:
Discover novel defense related materials/molecules.
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HQ: Haifa, Israel

What they do:
Predictive maintenance for power infrastructure.
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HQ: Baltimore, MD, United States

What they do:
An AI-operated logistics company.
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HQ: San Francisco, CA, United States

What they do:
Embodied Scientific Intelligence
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HQ: San Francisco, CA, United States

What they do:
Maximum information per experiment, minimum experiments per conclusion
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HQ: Lund, Sweden

What they do:
An AI bracelet that remembers your day and acts before you ask.
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HQ: San Francisco, CA, United States

What they do:
Motor cortex for physical AI
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HQ: San Francisco, CA, United States