Top Digital Health Startups in San Francisco

Quick facts:

3 employeesYC X26Early stage

Wellness & mental health Applied AI & ML Digital health & care

Lumeria

What they do:

Oura Ring for Skin

Quick facts:

3 employeesYC S26Early stage

Wellness & mental health Digital health & care

Million Marker

What they do:

23andMe for environmental exposures

Quick facts:

2 employeesYC S19Early stage

Medical devices & diagnostics Digital health & care

Auricle

What they do:

Neurostimulation implant to restore hearing & speech understanding

Quick facts:

2 employeesYC W21Early stage

Applied AI & ML Digital health & care Medical devices & diagnostics

InVision Medical Technology

What they do:

AI Diagnosis of Heart Disease

Quick facts:

2 employeesYC S22Early stage

Applied AI & ML AI agents & assistants Digital health & care

Hippo Scribe

What they do:

AI assisted documentation for PT/OT/SLP

Quick facts:

2 employeesYC W23Early stage

Digital health & care Logistics & supply chain

Unstatiq

What they do:

Single source of truth for your clinic's finances and supply chain.

Quick facts:

2 employeesYC W23Early stage

Wellness & mental health Digital health & care

Aidy

What they do:

Mobile app helping people better manage chronic health conditions

Quick facts:

2 employeesYC W24Early stage

Digital health & care Applied AI & ML

Copper Health

What they do:

Modern patient engagement and remote therapeutic monitoring platform

Quick facts:

2 employeesYC W24Early stage

Wellness & mental health Applied AI & ML Digital health & care

Adapted

What they do:

AI physical therapy for athletes

Quick facts:

2 employeesYC W24Early stage

Penciled

What they do:

AI front office assistant for physical therapy

Quick facts:

2 employeesYC W24Early stage

Digital health & care Robotics & drones

Entropy

What they do:

Autonomous intake and RCM for specialty clinics.

Quick facts:

2 employeesYC S24Early stage

Durate

What they do:

Automated physician scheduling

Quick facts:

2 employeesYC F24Early stage

Applied AI & ML Digital health & care Wellness & mental health

Vocality Health

What they do:

Voice AI for medical language translation

Quick facts:

2 employeesYC W25Early stage

Wellness & mental health Digital health & care

Amby Health

What they do:

The health coach that texts you first

Quick facts:

2 employeesYC W25Early stage

Applied AI & ML Sales & marketing Digital health & care E-commerce & retail

Cenote

What they do:

AI agents for conversational commerce

Quick facts:

2 employeesYC W25Early stage

Applied AI & ML Digital health & care Biotech & pharma

Frekil

What they do:

RWE Generation in minutes

Quick facts:

2 employeesYC X25Early stage

Applied AI & ML Cloud & infrastructure Digital health & care

Playgent

What they do:

Sandboxes for AI agents

Quick facts:

2 employeesYC S25Early stage

Applied AI & ML Digital health & care

Framewise Health

What they do:

AI-native patient engagement

Quick facts:

2 employeesYC X26Early stage

Archangel Health

What they do:

Infra to make AI safe enough to practice medicine

Quick facts:

2 employeesYC F26Early stage

Sutrix

What they do:

Turns EHR data into study-ready datasets for hospital research teams

Quick facts:

2 employeesYC F26Early stage

Insurance Applied AI & ML Digital health & care

Decent

What they do:

Your health plan should get better year-round. Not just once a year.

Quick facts:

2 employeesYC F26Early stage

Digital health & care Applied AI & ML

HealthSpark

What they do:

Empowering Physical Therapists to Go Independent

Quick facts:

1 employeesYC F24Early stage

Lattice Health

What they do:

Monitoring and governance for deployed medical imaging AI

Quick facts:

1 employeesYC X26Early stage

Carrot Fertility

What they do:

Customized fertility benefits for modern companies.

Quick facts:

YC S17Growth stage

Applied AI & ML Digital health & care Wellness & mental health

Scritch

What they do:

AI operating system for veterinary care

Quick facts:

YC W24Early stage

Digital health & care Biotech & pharma

Nxtcure Labs

What they do:

The full-stack AI CRO for drug discovery.

Quick facts:

YC F26Early stage

Digital health & care Developer tools

DrChrono

Acquired

What they do:

The essential platform for modern medical practices and patients.

Quick facts:

150 employeesYC W11Growth stageRemote

Yoneda Research

Quick facts:

30 employeesYC W20Early stage

Digital health & care Wellness & mental health

Truepill

Acquired

What they do:

API-connected healthcare infrastructure.

Quick facts:

1,300 employeesYC S17Growth stageRemote

Digital health & care Applied AI & ML

Memora Health

Acquired

What they do:

Digitize and Automate Complex Care Workflows

Quick facts:

115 employeesYC W18Early stage

Digital health & care Wellness & mental health Medical devices & diagnostics

Spire Health

Acquired

What they do:

Remote patient monitoring for lung disease patients.

Quick facts:

52 employeesYC W15Growth stage

Comprehend

Acquired

What they do:

SaaS to increase speed and quality of clinical trials.

Quick facts:

51 employeesYC W11Growth stage

Digital health & care Biotech & pharma

Science Exchange

Acquired

What they do:

Powering scientific outsourcing

Quick facts:

50 employeesYC S11Growth stageRemote

HeyDoctor

Acquired

What they do:

HeyDoctor provides online primary care (like refilling birth control,…

Quick facts:

50 employeesYC S18Early stage

Enzyme

Acquired

What they do:

Automating regulatory approval & compliance for life science companies

Quick facts:

32 employeesYC S17Early stageRemote