Quick facts:
HQ: Cambridge, MA, United States
Incorporated: 2025
Funding:
$4.11M · Equity · Jan 2026
Top Deep Tech Startups in Massachusetts
This list has 49 startups and was last updated on Oct 15, 2026. 6 of them are hiring right now. Biggest hubs: Boston (38), Cambridge (3), and Waltham (2). Largest teams: Ginkgo Bioworks, Raptor Maps, and SiPhox Health. Latest round: Finwave Semiconductor raised $15.5M (Oct 8, 2026).
49 startupsPage 2 of 2
Quick facts:
HQ: Southborough, MA, United States
Incorporated: 2026
Funding:
$4.1M · Equity · Jun 2026
Quick facts:
HQ: Boston, MA, United States
Incorporated: 2025
Funding:
$3M · Equity · Jan 2026
Quick facts:
HQ: Boston, MA, United States
Incorporated: 2025
Funding:
$2.6M · Equity · Jan 2026
Quick facts:
HQ: Groton, MA, United States
Funding:
$1.29M · Equity · Apr 2026
Quick facts:
HQ: Boston, MA, United States
Incorporated: 2023
Funding:
$1.28M · Debt · Apr 2026
Quick facts:
HQ: Stow, MA, United States
Incorporated: 2023
Funding:
$759K · Debt · Oct 2026
Gaiascope
Acquired
What they do:
SaaS that helps renewables & energy storage operate more profitably
Quick facts:
HQ: Boston, MA, United States
Bytebot
Acquired
What they do:
Bytebot is the open source container for AI desktop agents.
Quick facts:
HQ: Boston, MA, United States
Radix Labs
Shut down
What they do:
Operating systems for biology labs
Quick facts:
HQ: Boston, MA, United States
Airmada
Shut down
What they do:
Autonomous ground stations for drones
Quick facts:
HQ: Boston, MA, United States
Bensen
Shut down
What they do:
Online and phone ordering for restaurant takeout and delivery
Quick facts:
HQ: Boston, MA, United States
CO2Stats
Shut down
What they do:
Social and environmental web analytics. Acquired in December 2016.
Quick facts:
HQ: Boston, MA, United States
YC S08Early stage