What they do:
World's fastest and most optimal route optimization engine
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HQ: Ontario, CA, United States
Top Deep Tech Startups
This list has 1,861 startups and was last updated on Oct 15, 2026. 377 of them are hiring right now. Biggest hubs: San Francisco (704), New York (137), and Los Angeles (79). Largest teams: Breadfast, DoorDash, and EquipmentShare. Latest round: Scimplify raised $25M (Oct 15, 2026).
Survival statistics →1,040 open roles →
1,861 startupsPage 22 of 52
What they do:
Building the next generation food ingredient champion.
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What they do:
Detect cyber attacks on critical physical infrastructure
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What they do:
We stop cows from burping methane.
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HQ: San Francisco, CA, United States
What they do:
Vision-powered warehouse automation: maximizing performance and value
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HQ: Singapore
What they do:
Limitless Real Estate
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HQ: San Francisco, CA, United States
What they do:
Manufacturing more proteins with AI.
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HQ: San Francisco, CA, United States
What they do:
Plaid for Commercial Real Estate
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HQ: Boston, MA, United States
What they do:
Building persistent, high-performance infrastructure in the sky
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HQ: Seattle, WA, United States
What they do:
Developing long-lasting drug formulations 50% faster
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HQ: Sacramento, CA, United States
What they do:
Creating new protein-based drugs at scale
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What they do:
Building the next Procore
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HQ: Santa Barbara, CA, United States
What they do:
Tracking methane emissions with satellites
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HQ: Remote
What they do:
Voice AI for Automotive
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HQ: London, United Kingdom
What they do:
We make robots that move boxes in warehouses
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HQ: San Francisco, CA, United States
Consus
Hiring
What they do:
The fastest and cheapest way to use AI with ITAR or CUI data.
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HQ: San Francisco, CA, United States
What they do:
The memory computer for your digital life.
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HQ: San Francisco, CA, United States
What they do:
The personal AI agent for Korea.
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HQ: San Francisco, CA, United States
What they do:
Hardware-Aware AI for Embedded Software
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HQ: San Francisco, CA, United States
What they do:
Your phone finally has someone to run it. Plug in Blue, just ask.
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HQ: San Francisco, CA, United States
What they do:
Mass-producing and financing micro data center incredibly quickly.
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HQ: San Francisco, CA, United States
What they do:
Rocket cargo delivery to contested environments
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HQ: Los Angeles, CA, United States
AptDeco
Hiring
What they do:
AptDeco is the easiest way to buy and sell used furniture
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HQ: New York, NY, United States
YC W14Growth stage
What they do:
"Name Your Price" for products
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HQ: New York, NY, United States
What they do:
Sourcing investment real estate
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HQ: New York, NY, United States
What they do:
Enabling T cell immunotherapy discovery, development and manufacturing
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HQ: San Francisco, CA, United States
What they do:
iPhone-based driver monitoring for commercial fleets.
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HQ: San Francisco, CA, United States
Spice Data
Hiring
What they do:
Restaurant Data for the Enterprise
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HQ: San Francisco, CA, United States
YC S19Early stage
What they do:
AI that tells mining companies where to mine to maximize profits
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Minimum
Hiring
What they do:
Helping corporates achieve Net Zero through tech solutions.
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HQ: London, United Kingdom
YC S20Early stage
What they do:
Elevating mental health to be a part of your daily coffee ritual.
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HQ: San Francisco, CA, United States
What they do:
Autonomous street sweeping as a service by retro-fitting vehicles
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HQ: San Francisco, CA, United States
What they do:
Software for procurement departments to find suppliers 10x faster
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What they do:
A platform to make artificial viruses as cancer therapeutics.
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HQ: New York, NY, United States
What they do:
Search and automation for engineer-to-order companies
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HQ: San Francisco, CA, United States
What they do:
Making 'REAL' Cow and Human Milk!
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HQ: Boston, MA, United States