What they do:
Managed Sales Email Delivery For Cold Outreach
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Top Deep Tech Startups
This list has 1,861 startups and was last updated on Oct 15, 2026. 377 of them are hiring right now. Biggest hubs: San Francisco (704), New York (137), and Los Angeles (79). Largest teams: Breadfast, DoorDash, and EquipmentShare. Latest round: Scimplify raised $25M (Oct 15, 2026).
Survival statistics →1,040 open roles →
1,861 startupsPage 23 of 52
What they do:
The Operating System of the construction industry
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What they do:
Building self-programming machines
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What they do:
Your biopharma team, from molecule design to portfolio strategy
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HQ: San Francisco, CA, United States
What they do:
AI for modern automotive dealerships
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What they do:
Hypersonic space plane that can take-off from any location and weather
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HQ: Dayton, OH, United States
What they do:
Empowering every doctor and every patient to participate in research
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HQ: New York, NY, United States
Sirdab
Hiring
What they do:
Cloud warehousing & supply chain platform in MENA
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HQ: Riyadh, Saudi Arabia
YC W23Early stage
Automat
Hiring
What they do:
Agentic automation that understands context, recovers, and improves.
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HQ: San Francisco, CA, United States
YC W23Growth stage
What they do:
Gen-AI Designed Enzymes for Pharmaceutical Innovation
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HQ: Boston, MA, United States
What they do:
AI for ASIC Design Verification
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HQ: San Francisco, CA, United States
What they do:
Deliver genes to any cell with AI
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HQ: London, United Kingdom
What they do:
Combination therapeutics for the world's toughest diseases
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HQ: Remote
What they do:
Farm Genetics Made Easy - Using DNA and Software
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HQ: Asheville, NC, United States
What they do:
Unified flight software and hardware for the mission of tomorrow
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HQ: San Francisco, CA, United States
What they do:
Aggregating Spot Freight Opportunities for Carriers
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HQ: Seattle, WA, United States
What they do:
Starbucks app for restaurants
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HQ: San Francisco, CA, United States
What they do:
Gen AI molecular simulations that reproduce wetlab results
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HQ: San Francisco, CA, United States
Spaceium Inc
Hiring
What they do:
In-Space Refueling
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What they do:
Automating airport baggage handling with robots.
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HQ: San Francisco, CA, United States
YC S24Early stage
What they do:
Humanoid robots that do your chores for the price of an iPhone!
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HQ: London, United Kingdom
What they do:
AI Report Generation for Engineering & Environmental Review
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HQ: London, United Kingdom
What they do:
Simulation software used by leading battery and automotive companies
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HQ: Remote
Partcl
Hiring
What they do:
Design a chip in minutes
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HQ: San Francisco, CA, United States
YC X25Early stage
What they do:
Voice AI teams for medicare agencies.
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HQ: San Francisco, CA, United States
What they do:
Financial OS for Modern Fleets
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What they do:
Building lunar landers
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HQ: London, United Kingdom
What they do:
A Roomba for weeds on a farm.
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HQ: Seattle, WA, United States
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AI-powered robotics for scientific lab automation.
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HQ: San Francisco, CA, United States
What they do:
chrt is a logistics platform for time-critical shipping
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HQ: Los Angeles, CA, United States
IronLedger.ai
Hiring
What they do:
AI-enabled Corporate Cards and Invoice Processing for Real Estate
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HQ: New York, NY, United States
YC S25Early stage
Relling
Hiring
What they do:
deploying the first billion robots for manufacturing
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HQ: San Francisco, CA, United States
YC S25Early stage
What they do:
The GD&T Analysis Platform for Engineering Drawings
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HQ: San Francisco, CA, United States
Juxta
Hiring
What they do:
Building a GPS alternative 100x more powerful with no hardware needed.
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HQ: San Francisco, CA, United States
YC S25Early stage
What they do:
AI agents for power grid planning 🦑
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HQ: London, United Kingdom
Zymbly
Hiring
What they do:
The decision-support layer for aviation ops teams to know what to do…
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HQ: London, United Kingdom
YC W26Early stage