What they do:
Generate fast, reliable APIs for any platform
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HQ: San Francisco, CA, United States
Top Startups in the United States
This list has 6,416 startups and was last updated on Oct 16, 2026. 1,188 of them are hiring right now. Biggest hubs: San Francisco (3,181), New York (859), and Los Angeles (198). Largest teams: DoorDash, Stripe, and Airbnb. Latest round: High Street Holdco raised $3.5M (Oct 15, 2026).
6,416 startupsPage 55 of 179
What they do:
Ultimate AI Math Problem Solver to Revolutionize Personalized Learning
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HQ: San Francisco, CA, United States
What they do:
Tools for agent verification
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HQ: San Francisco, CA, United States
What they do:
Starbucks app for restaurants
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HQ: San Francisco, CA, United States
What they do:
Gen AI molecular simulations that reproduce wetlab results
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HQ: San Francisco, CA, United States
What they do:
Automating police paperwork
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HQ: San Francisco, CA, United States
What they do:
Faster, more profitable background checks with AI
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HQ: Los Angeles, CA, United States
What they do:
Unified Hardware Control and Data Processing Software
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HQ: Denver, CO, United States
What they do:
Automating airport baggage handling with robots.
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HQ: San Francisco, CA, United States
YC S24Early stage
What they do:
Stormy runs the office so your crew can run the work.
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HQ: San Francisco, CA, United States
What they do:
AI agents that handles complex billing and revenue
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HQ: San Francisco, CA, United States
What they do:
At-cost preventive health: Labs, Scans, Genetics, Supplements and Rx
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HQ: San Francisco, CA, United States
What they do:
Powerful quantitative forecasting models
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HQ: New York, NY, United States
Emergent
Hiring
What they do:
AI app builder that turns your ideas into monetizable software.
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HQ: San Francisco, CA, United States
YC S24Growth stage
What they do:
Helping hospitals identify and prevent avoidable harm using AI
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HQ: San Francisco, CA, United States
What they do:
The most powerful sandboxes for AI Agents
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HQ: San Francisco, CA, United States
What they do:
Voice AI sims for next-gen employee training
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HQ: New York, NY, United States
What they do:
coaching agents for athletes
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HQ: Boston, MA, United States
What they do:
Find and move money after a death
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HQ: Salt Lake City, UT, United States
What they do:
AI app builder for creating and launching iPhone apps
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HQ: San Francisco, CA, United States
What they do:
Software for AI-powered traffic lights
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HQ: San Francisco, CA, United States
Partcl
Hiring
What they do:
Design a chip in minutes
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HQ: San Francisco, CA, United States
YC X25Early stage
What they do:
Voice AI teams for medicare agencies.
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HQ: San Francisco, CA, United States
What they do:
Frontier Data
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HQ: San Francisco, CA, United States
Wildcard
Hiring
What they do:
AEO/GEO for E-Commerce and Retail
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HQ: San Francisco, CA, United States
YC W25Early stage
What they do:
A Roomba for weeds on a farm.
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HQ: Seattle, WA, United States
What they do:
AI native financial institution
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HQ: San Francisco, CA, United States
What they do:
AI-powered robotics for scientific lab automation.
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HQ: San Francisco, CA, United States
What they do:
Encrypted AI with verifiable privacy
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HQ: San Francisco, CA, United States
What they do:
Turn scattered data into one platform for decision-making
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HQ: San Francisco, CA, United States
What they do:
chrt is a logistics platform for time-critical shipping
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HQ: Los Angeles, CA, United States
What they do:
AI agents for risk-bearing healthcare organizations
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HQ: San Francisco, CA, United States
Adaptional
Hiring
What they do:
AI-powered insurance claims review
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HQ: San Francisco, CA, United States
YC S25Early stage
What they do:
AI advisor for retail investors
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HQ: San Francisco, CA, United States
What they do:
The E2E testing layer for AI-driven development
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HQ: San Francisco, CA, United States
What they do:
Agents that learn your company and work 24/7
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HQ: San Francisco, CA, United States