What they do:
Agents that learn your company and work 24/7
Quick facts:
HQ: San Francisco, CA, United States
Top Startups in the United States
This list has 6,379 startups and was last updated on Oct 15, 2026. 1,190 of them are hiring right now. Biggest hubs: San Francisco (3,173), New York (858), and Los Angeles (197). Largest teams: DoorDash, Stripe, and Airbnb. Latest round: Lungpacer Medical raised $7.83M (Oct 14, 2026).
6,379 startupsPage 56 of 178
Proliferate
Hiring
What they do:
Do your life's work with agents
Quick facts:
HQ: San Francisco, CA, United States
YC S25Early stage
IronLedger.ai
Hiring
What they do:
AI-enabled Corporate Cards and Invoice Processing for Real Estate
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HQ: New York, NY, United States
YC S25Early stage
Relling
Hiring
What they do:
deploying the first billion robots for manufacturing
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HQ: San Francisco, CA, United States
YC S25Early stage
What they do:
AI agents for E2E testing across mobile & web
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Airline customer service, fully automated.
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HQ: San Francisco, CA, United States
What they do:
The GD&T Analysis Platform for Engineering Drawings
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HQ: San Francisco, CA, United States
What they do:
Browser infra for AI agents: sessions, auth, proxies, payments
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HQ: San Francisco, CA, United States
Juxta
Hiring
What they do:
Building a GPS alternative 100x more powerful with no hardware needed.
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HQ: San Francisco, CA, United States
YC S25Early stage
What they do:
AI to run behavioral health programs better
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HQ: Chicago, IL, United States
What they do:
AI that creates and runs ads, end-end
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HQ: San Francisco, CA, United States
What they do:
Your Personal AI for everyday work. Lives in your texts.
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HQ: New York, NY, United States
Soren
Hiring
What they do:
The AI Transformation Company
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HQ: San Francisco, CA, United States
YC F25Early stage
What they do:
Casey is an AI-native commercial insurance brokerage
Quick facts:
HQ: San Francisco, CA, United States
What they do:
API for unlimited, durable, real-time streams
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HQ: San Francisco, CA, United States
What they do:
Simulate your customers with AI agents
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HQ: Boston, MA, United States
What they do:
Adaptive training coach for runners, cyclists, and triathletes
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HQ: San Francisco, CA, United States
What they do:
Trade with superhuman instinct
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HQ: San Francisco, CA, United States
What they do:
AI Infra for real-time vision applications
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HQ: San Francisco, CA, United States
VOYGR
Hiring
What they do:
Real-world place intelligence for AI apps and agents
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HQ: San Francisco, CA, United States
YC W26Early stage
What they do:
Manipulate Anything Robot
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HQ: San Francisco, CA, United States
What they do:
A new kind of camera that can see through walls.
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HQ: San Francisco, CA, United States
Cardinal
Hiring
What they do:
Revenue Agents for GTM teams
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HQ: San Francisco, CA, United States
YC W26Early stage
Totalis
Hiring
What they do:
derivative layer for prediction markets
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HQ: New York, NY, United States
YC X26Early stage
What they do:
Agents that run short-term rental operations end-to-end
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HQ: San Francisco, CA, United States
What they do:
Real-world sandboxes to test and train AI agents
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HQ: San Francisco, CA, United States
What they do:
Live Evaluation Arenas for Financial Work
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HQ: New York, NY, United States
What they do:
The first wearable that reads your emotions to enhance your EQ.
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HQ: San Francisco, CA, United States
Plena Health
Hiring
What they do:
Plena is the AI operating system for specialty medical practices
Quick facts:
HQ: San Francisco, CA, United States
YC X26Early stage
AgentPhone
Hiring
What they do:
Phone Numbers for AI Agents
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HQ: San Francisco, CA, United States
YC X26Early stage
What they do:
Find and engage with desperate buyers across LinkedIn, Email, and X
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HQ: San Francisco, CA, United States
What they do:
Scale AI scientists whose own breakthroughs accelerate the next.
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HQ: San Francisco, CA, United States
What they do:
Automated LiveOps for Game Studios
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HQ: San Francisco, CA, United States
What they do:
Autonomous Customer Operations
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HQ: San Francisco, CA, United States
What they do:
The AI-native trading company: factory prices, delivered, one number
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HQ: San Francisco, CA, United States
What they do:
The AI BPO for financial servies, run by computer-use agents
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HQ: San Francisco, CA, United States