What they do:
AI agents to enroll providers with payors
Quick facts:
HQ: San Francisco, CA, United States
Top Deep Tech Startups in California
This list has 849 startups and was last updated on Oct 16, 2026. 201 of them are hiring right now. Biggest hubs: San Francisco (705), Los Angeles (79), and San Diego (7). Largest teams: DoorDash, GrubMarket, and Instacart. Latest round: hiyo raised $20.8M (Oct 15, 2026).
849 startupsPage 13 of 24
What they do:
AI agent for construction drawings review
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Building low-cost cruise missiles
Quick facts:
HQ: Los Angeles, CA, United States
What they do:
Datadog for robots
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Propaya is an AI-powered commercial real estate intelligence platform that transforms leases and property documents into structured, actionable data. It…
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Autonomous intake and RCM for specialty clinics.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Making procurement easy
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Your AI scheduling assistant for construction
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Quick-turn bent tube shop for aerospace, energy, industrials
Quick facts:
HQ: Los Angeles, CA, United States
What they do:
AI-native remote operations center for hardware fleets
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI personal assistant for in-home sales
Quick facts:
HQ: San Francisco, CA, United States
What they do:
All-In-One AI Growth Partner. Built for Trades.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Physics-based foundation models for CAD optimization.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
End-to-end Simulation for Defense Autonomy
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Self learning computer use agent for developers
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI-native ERP for food wholesalers
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Building intellectually curious AI
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Building tiny frontier AI models that run on edge devices
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI-Native Data Center Engineering
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The Cursor for Chip Design - Delivering Silicon-Ready Chip Designs…
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Waymo for excavators
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI-native ERP for manufacturers
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Delivering AI-powered situational awareness in tactical environments.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Powering tomorrow's industrial revolution in space
Quick facts:
HQ: San Diego, CA, United States
What they do:
Fast Physics Simulations for Rapid Design and Real Time Control
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Autonomous OS for healthcare
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Multimodal foundation models to predict uncollected patient biology
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI teammates for logistics
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Infrastructure for Autonomous Science
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI native radars for self-driving cars
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Foundation models for 24/7 Earth Observation
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The secure training data R&D engine for physical AI
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The robot workforce for infrastructure
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Automating dexterous tasks in warehouses with AI-powered robots
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Keeping contractors on the job site, not behind a desk.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Drones that clear clouds over solar farms and weaken hurricanes
Quick facts:
HQ: San Francisco, CA, United States