What they do:
Flying motorcycles
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HQ: Los Angeles, CA, United States
Top Deep Tech Startups in California
This list has 846 startups and was last updated on Oct 15, 2026. 201 of them are hiring right now. Biggest hubs: San Francisco (704), Los Angeles (79), and San Diego (7). Largest teams: DoorDash, GrubMarket, and Instacart. Latest round: Circularity Fuels raised $8.79M (Oct 14, 2026).
846 startupsPage 7 of 24
What they do:
IndustrialNext builds the AI brain for manufacturing –…
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HQ: San Francisco, CA, United States
What they do:
A single point integration for secure and automated EV charging.
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HQ: San Francisco, CA, United States
What they do:
The largest freight scheduling network in the industry.
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HQ: San Francisco, CA, United States
Metalware
Hiring
What they do:
Firmware cybersecurity
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HQ: San Francisco, CA, United States
Relari
Hiring
What they do:
Building dexterous robots that learn from human biomechanics
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HQ: San Francisco, CA, United States
Conductor Quantum
Hiring
What they do:
AI that operates quantum computers for scientific discovery
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HQ: San Francisco, CA, United States
Outerport
Hiring
What they do:
Design automation for industrial electrical controls
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HQ: San Francisco, CA, United States
What they do:
Manufacturing the most powerful chips, 15x faster
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HQ: San Francisco, CA, United States
Adam
Hiring
What they do:
AI Powered CAD
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HQ: San Francisco, CA, United States
Artifact
Hiring
What they do:
An Collaborative, AI-native IDE for Hardware Engineers
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HQ: Los Angeles, CA, United States
What they do:
Robots, parts & RL envs & evals - delivered in 48 hrs / pickup in SF.
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HQ: San Francisco, CA, United States
Darwin
Hiring
What they do:
Robots to build civilization
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HQ: San Francisco, CA, United States
General Astronautics
Hiring
What they do:
Superintelligent space Robots
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HQ: San Francisco, CA, United States
Fort
Hiring
What they do:
Strength Tracking Wearable
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HQ: San Francisco, CA, United States
Dispatch
Hiring
What they do:
Satellites for Manufacturing in Space
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HQ: San Francisco, CA, United States
Eden Robotics
Hiring
What they do:
Autonomous services for humanity.
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HQ: San Francisco, CA, United States
ProvenMetal
Hiring
What they do:
AI-native electronics manufacturing for the American industrial base
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HQ: San Francisco, CA, United States
What they do:
using ultrasonics + ml to analyze fluid behavior at infrastructure…
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HQ: San Francisco, CA, United States
What they do:
Organizing the world's inventory.
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HQ: San Francisco, CA, United States
What they do:
Portable cryoablation to prevent cervical cancer
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HQ: San Francisco, CA, United States
Versable
Hiring
What they do:
AI powered product description enhancement for the auto parts industry
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HQ: San Francisco, CA, United States
Scout
Hiring
What they do:
AI insights for consumer products
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HQ: San Francisco, CA, United States
What they do:
Field-First AI for home services
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HQ: San Francisco, CA, United States
ArchiLabs
Hiring
What they do:
AI Data Center Design
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HQ: San Francisco, CA, United States
Dalus
Hiring
What they do:
AI-Powered Hardware System Design Software
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HQ: San Francisco, CA, United States
What they do:
Automation Foundation Models For Tiny Devices
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HQ: San Francisco, CA, United States
Hemut
Hiring
What they do:
AI-powered operating system for trucking companies.
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HQ: Fresno, CA, United States
BootLoop
Hiring
What they do:
Firmware in minutes, not months - rigorously tested on real hardware
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HQ: San Francisco, CA, United States
b12 Labs
Hiring
What they do:
Making hard molecules for Pharma and Biotech
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HQ: San Francisco, CA, United States
What they do:
Replacing the restaurant phone line with Voice AI
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HQ: San Francisco, CA, United States
burnt
Hiring
What they do:
Agentic Operating System for Food Supply Chain
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HQ: San Francisco, CA, United States
Exonic
Hiring
What they do:
Exonic is an AI-native cell and gene therapeutics company.
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HQ: San Francisco, CA, United States
Lightberry
Hiring
What they do:
Robots with soul
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HQ: San Francisco, CA, United States
Asimov
Hiring
What they do:
Real-world human movement data for humanoid robots
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HQ: San Francisco, CA, United States
Visibl Semiconductors
Hiring
What they do:
Custom silicon for power electronics
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HQ: San Francisco, CA, United States