Partcl
Hiring
What they do:
Design a chip in minutes
Quick facts:
HQ: San Francisco, CA, United States
YC X25Early stage
Top Deep Tech Startups in California
This list has 849 startups and was last updated on Oct 16, 2026. 201 of them are hiring right now. Biggest hubs: San Francisco (705), Los Angeles (79), and San Diego (7). Largest teams: DoorDash, GrubMarket, and Instacart. Latest round: hiyo raised $20.8M (Oct 15, 2026).
849 startupsPage 10 of 24
What they do:
Voice AI teams for medicare agencies.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI-powered robotics for scientific lab automation.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
chrt is a logistics platform for time-critical shipping
Quick facts:
HQ: Los Angeles, CA, United States
Relling
Hiring
What they do:
deploying the first billion robots for manufacturing
Quick facts:
HQ: San Francisco, CA, United States
YC S25Early stage
What they do:
The GD&T Analysis Platform for Engineering Drawings
Quick facts:
HQ: San Francisco, CA, United States
Juxta
Hiring
What they do:
Building a GPS alternative 100x more powerful with no hardware needed.
Quick facts:
HQ: San Francisco, CA, United States
YC S25Early stage
What they do:
Manipulate Anything Robot
Quick facts:
HQ: San Francisco, CA, United States
What they do:
A new kind of camera that can see through walls.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Agents that run short-term rental operations end-to-end
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The first wearable that reads your emotions to enhance your EQ.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Autonomous Customer Operations
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The AI-native trading company: factory prices, delivered, one number
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The AI BPO for financial servies, run by computer-use agents
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The company brain for construction companies
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The most capable American-made humanoid robot for $1,688
Quick facts:
HQ: San Francisco, CA, United States
Operon
Hiring
What they do:
Agentic data layer for manufacturing & process industries.
Quick facts:
HQ: San Francisco, CA, United States
YC S26Early stage
Lamb Labs
Hiring
What they do:
Lightning fast chips with hardcoded AI models
Quick facts:
HQ: San Francisco, CA, United States
YC S26Early stage
What they do:
Synvivia applies chemical control over cell behavior
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Nuvola is transforming battery manufacturing, making EV batteries…
Quick facts:
HQ: Los Angeles, CA, United States
What they do:
Smart gels for local drug delivery to the gut
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Shiru leverages ML to create proteins to feed the world sustainably.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI-Native Restaurant POS
Quick facts:
HQ: San Francisco, CA, United States
What they do:
We make bacteria and plants that clean up pollution.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Developing milk-inspired therapeutics for infectious diseases
Quick facts:
HQ: Davis, CA, United States
What they do:
Make diesel semi trucks hybrid-electric
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The spatial AI to plan, build and maintain the world's infrastructure
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Enzyme design models.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Building a nervous system for the atmosphere
Quick facts:
HQ: San Francisco, CA, United States
What they do:
We build floating solar data centers
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Connect with hotel owners around the world.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Streamlining Data Capture to Report Creation for Heavy Industries
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Applied research lab for hardware design
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The world's first AI-maximalist pharma company
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI powered brokerage reducing residential rental commissions in NYC…
Quick facts:
HQ: San Francisco, CA, United States
What they do:
.
Quick facts:
HQ: San Francisco, CA, United States