What they do:
AI native real-estate appraisal firm
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HQ: San Francisco, CA, United States
Top Deep Tech Startups in California
This list has 846 startups and was last updated on Oct 15, 2026. 201 of them are hiring right now. Biggest hubs: San Francisco (704), Los Angeles (79), and San Diego (7). Largest teams: DoorDash, GrubMarket, and Instacart. Latest round: Circularity Fuels raised $8.79M (Oct 14, 2026).
846 startupsPage 11 of 24
What they do:
Operational Intelligence for Global Logistics
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HQ: San Francisco, CA, United States
What they do:
AI benchmarks that measure general intelligence and inspire new ideas
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HQ: San Francisco, CA, United States
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Robots that run autonomous depots for autonomous fleets.
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HQ: San Francisco, CA, United States
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Evolutionary intelligence for autoimmune disease
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HQ: San Francisco, CA, United States
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AI that turns any camera to an autonomous worker with real-time vision
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HQ: San Francisco, CA, United States
What they do:
Annotations for robotics data
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HQ: San Francisco, CA, United States
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We're building robot birds for surveillance.
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HQ: Los Angeles, CA, United States
What they do:
Nervous System for Physical AI
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HQ: San Francisco, CA, United States
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Building drone swarms that hunt hidden enemies.
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HQ: San Francisco, CA, United States
What they do:
AI-native procurement services for the physical economy
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HQ: San Francisco, CA, United States
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Unmanned cargo airplanes
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HQ: Los Angeles, CA, United States
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Microgrids in a box built anywhere in days
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HQ: San Francisco, CA, United States
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Automating away manual admin for food distributors: texts to ERP
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HQ: San Francisco, CA, United States
What they do:
Robots for high skilled labor powering AI infrastructure
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HQ: San Francisco, CA, United States
What they do:
Real-time cloud inference for robotics.
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HQ: San Francisco, CA, United States
What they do:
Enable robots to operate safely in the real world.
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HQ: San Francisco, CA, United States
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Cutting edge hydrofoil systems for boatbuilders
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HQ: San Francisco, CA, United States
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Last-mile delivery for perishables.
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HQ: San Francisco, CA, United States
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Growing micro-organs to find new drugs
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HQ: San Francisco, CA, United States
What they do:
Platform to automate manual back-office work
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HQ: San Francisco, CA, United States
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The AI platform for CRE investment teams
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HQ: San Francisco, CA, United States
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The Data Platform for Mission‑Critical Systems
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HQ: San Francisco, CA, United States
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AI chips for ultra-fast training and inference
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HQ: San Francisco, CA, United States
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AI back office for food product quality teams
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HQ: Los Angeles, CA, United States
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Foundation Model for Chemical Manufacturing
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HQ: San Francisco, CA, United States
What they do:
Batteries and solar for $0 upfront to help businesses save money
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HQ: San Francisco, CA, United States
What they do:
Config Management for Robotics
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HQ: San Francisco, CA, United States
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Gigascale Nanomanufacturing
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HQ: San Francisco, CA, United States
What they do:
A stealth mode startup.
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HQ: San Francisco, CA, United States
What they do:
Engineering microbes for miners to unlock billions in trapped metal
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HQ: San Francisco, CA, United States
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Datadog for industrial robots
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HQ: San Francisco, CA, United States
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The new American reinsurance company.
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HQ: San Francisco, CA, United States
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Robots that repair roads
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HQ: San Francisco, CA, United States
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We assemble PCBs in under 48 hours for quantities under 10
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HQ: San Francisco, CA, United States
What they do:
Open-source semi-humanoid dev kit → home data → autonomy → 20h/wk
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HQ: Los Angeles, CA, United States