Ready
Hiring
What they do:
Collaborative platform for optimizing regulated utilities such as…
Quick facts:
HQ: San Francisco, CA, United States
Top Deep Tech Startups in California
This list has 846 startups and was last updated on Oct 15, 2026. 201 of them are hiring right now. Biggest hubs: San Francisco (704), Los Angeles (79), and San Diego (7). Largest teams: DoorDash, GrubMarket, and Instacart. Latest round: Circularity Fuels raised $8.79M (Oct 14, 2026).
846 startupsPage 2 of 24
Shepherd
Hiring
What they do:
Modernizing commercial insurance
Quick facts:
HQ: San Francisco, CA, United States
Cambio
Hiring
What they do:
AI-native commercial real estate operations
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Home boxing gym with motion trackers that compute punches and reps.
Quick facts:
HQ: Los Angeles, CA, United States
What they do:
Cheese and dairy products from plant-derived dairy proteins
Quick facts:
HQ: San Francisco, CA, United States
Astro Mechanica
Hiring
What they do:
Supersonics for the new Jet Age
Quick facts:
HQ: San Francisco, CA, United States
Verge Genomics
Hiring
What they do:
We use human data and AI to develop better drugs faster.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Lygos (W16) built and commercialized sustainable, high-performance…
Quick facts:
HQ: San Francisco, CA, United States
Agave
Hiring
What they do:
Applied AI for Construction
Quick facts:
HQ: San Francisco, CA, United States
Icarus
Hiring
What they do:
Stratospheric birds for defense
Quick facts:
HQ: Los Angeles, CA, United States
What they do:
Petcube is on the mission to improve lives of pets and pet owners…
Quick facts:
HQ: San Francisco, CA, United States
Reach
Hiring
What they do:
Long range, wireless energy distribution that scales
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Heart makes electric airplanes with an all-electric range of 250 miles
Quick facts:
HQ: Los Angeles, CA, United States
What they do:
Enterprise software to quantify cost-effective decarbonization…
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Building robotic mushroom farms
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The operating system powering ecommerce fulfillment
Quick facts:
HQ: Los Angeles, CA, United States
What they do:
Healthy packaged fresh food
Quick facts:
HQ: Los Angeles, CA, United States
What they do:
We make high definition radar allowing self-driving cars to see in…
Quick facts:
HQ: San Francisco, CA, United States
Overview
Hiring
What they do:
Reshaping industrial quality with AI, hardware, and software
Quick facts:
HQ: San Francisco, CA, United States
What they do:
We make EV charging as simple and reliable as LED lights
Quick facts:
HQ: San Francisco, CA, United States
Living Carbon
Hiring
What they do:
maximizing biomass on low quality land
Quick facts:
HQ: San Francisco, CA, United States
Nash
Hiring
What they do:
Nash is the digital logistics infrastructure for commerce
Quick facts:
HQ: San Francisco, CA, United States
Vooma
Hiring
What they do:
Automation platform for logistics
Quick facts:
HQ: San Francisco, CA, United States
Hub
Hiring
What they do:
Real-world training data for frontier AI labs and robotics.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Sales software for roofers. Aerial measurements + proposals in seconds
Quick facts:
HQ: San Francisco, CA, United States
What they do:
We grow cells for biotech companies.
Quick facts:
HQ: San Francisco, CA, United States
BlueCargo
Hiring
What they do:
The automated solution for complex freight transactions.
Quick facts:
HQ: Los Angeles, CA, United States
Flai
Hiring
What they do:
We Bring Customers to Your Dealership
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Order ahead at restaurants and get rewards with friends.
Quick facts:
HQ: San Francisco, CA, United States
Eze
Hiring
What they do:
The easiest way to track, buy, and sell your company’s tech — all in…
Quick facts:
HQ: San Francisco, CA, United States
GETASAP
Hiring
What they do:
AI-Native Fresh Produce Logistics
Quick facts:
HQ: San Francisco, CA, United States
Vori
Hiring
What they do:
Vori is a modern operating system for supermarkets
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Predictive battery management software for electrified fleets
Quick facts:
HQ: San Francisco, CA, United States
Axle Health
Hiring
What they do:
Scheduling and workforce management SaaS for home healthcare providers
Quick facts:
HQ: Los Angeles, CA, United States
Two Dots
Hiring
What they do:
AI fraud prevention and underwriting agent
Quick facts:
HQ: San Francisco, CA, United States
Weave Robotics
Hiring
What they do:
Practical and delightful home robots
Quick facts:
HQ: San Francisco, CA, United States